Skip to main content

Advertisement

Log in

Reasons for Nonadherence to Psychiatric Medication and Cardiovascular Risk Factors Treatment Among Latino Bipolar Disorder Patients Living in Puerto Rico: A Qualitative Study

  • Original Paper
  • Published:
Community Mental Health Journal Aims and scope Submit manuscript

Abstract

Latinos with bipolar disorder (BD) have a high rate of nonadherence to psychiatric medication and treatment for other medical conditions such as cardiovascular disease (CVD) risk factors than non-Latinos with BD. The aim of this study is to identify patients’ perspectives on the reasons for nonadherence to psychiatric medication and for CVD risk factors conditions in outpatients with BD. Three focus group sessions were held for a total of 22 adults ranging from 23 to 60 years old. Participants had BD, Type I/II and CVD risk factors. Audio-recordings of focus groups were transcribed and a content analysis was performed. Reasons identified as barriers to adherence were somewhat different for BD medications in comparison to CVD risk factors suggesting the need for integrated interventions targeting these barriers to adherence for both BD and CVD risk factors.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Acosta, F. J., Hernández, J. L., Pereira, J., Herrera, J., & Rodríguez, C. J. (2012). Medication adherence in schizophrenia. World J Psychiatr, 2, 74–82. https://doi.org/10.5498/wjp.v2.i5.74.

    Article  PubMed  Google Scholar 

  • Adams, O. P., & Carter, A. O. (2011). Knowledges, attitudes, practices, and barriers reported by patients receiving diabetes and hypertension primary health care in Barbados: A focus group. BMC Family Practice, 12, 135.

    Article  PubMed  PubMed Central  Google Scholar 

  • Alegria, M., Sribney, W., & Mulvaney-Day, N. (2007). Social cohesion, social support and health among Latinos in the United States. Social Science & Medicine, 64, 477–495.

    Article  Google Scholar 

  • Carliner, H., Collins, P. Y., Cabassa, L. J., McNallen, A., Joestl, S. S., & Lewis-Fernández, R. (2014). Prevalence of cardiovascular risk factors among racial and ethnic minorities with schizophrenia spectrum and bipolar disorders: A critical literature review. Comprehensive Psychiatry, 55, 233–247.

    Article  PubMed  Google Scholar 

  • Champion, V. L., & Skinner, C. S. (2002). The health belief model. In K. Glanz, B. K. Rimer & K. Viswanath (Eds.), Health behavior and health education: Theory, research and practice (pp. 45–65). San Francisco: Jossey-Bass.

    Google Scholar 

  • Cho, J. Y., & Lee, E.-H. (2014). Reducing confusion about grounded theory and qualitative content analysis: Similarities and differences. Qualitative Report, 19, 1–20.

    Google Scholar 

  • Clatworthy, J., Bowskill, R., Rank, T., & Parham, R. (2007). Adherence to medication in bipolar disorder: A qualitative study exploring the role of the patients’ beliefs about the condition and its treatment. Bipolar Disorders, 9, 656–664.

    Article  PubMed  Google Scholar 

  • Creswell, J. (2013). Qualitative inquiry and research design: Choosing among five approaches (3rd edn.). Los Angeles: Sage Publications, Inc.

    Google Scholar 

  • Daviglus, M., Prizada, A., & Talavera, G. A. (2014). Cardiovascular disease risk factors in the Hispano/Latino population: Lessons from the Hispanic community health study/study of Latinos (HCHS/SOL). Progress in Cardiovascular Diseases, 57, 230–236. https://doi.org/10.1016/j.pcad.2014.07.006.

    Article  PubMed  Google Scholar 

  • Depp, C. A., Lebowitz, B. D., Patterson, T. L., Lacro, J. P., & Jeste, D. V. (2007). Medication adherence skills training for middle-aged and elderly adults with bipolar disorder: Development and pilot study. Bipolar Disorders, 9, 636–645.

    Article  PubMed  Google Scholar 

  • Elo, S., & Kyngäs, H. (2008). The qualitative content analysis process. Journal of Advanced Nursing, 62, 107–115.

    Article  PubMed  Google Scholar 

  • Fiedorowicz, J. G., Palagummi, N. M., Forman-Hoffman, V. L., Miller, del D., & Haynes, W. G. (2008). Elevated prevalence of obesity, metabolic syndrome, and cardiovascular risk factors in bipolar disorder. Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists, 20, 131–137.

    Article  Google Scholar 

  • García-Portilla, M., Saiz, P., Bascaran, M. T., Martínez, S., Benabarre, A., Sierra, P., et al. (2009). Cardiovascular risk in patients with bipolar disorder. Journal of Affective Disorders, 115, 302–308.

    Article  PubMed  Google Scholar 

  • Gaudiano, B. A., Weinstock, L. M., & Miller, I. W. (2008). Improving treatment adherence in bipolar disorder: A review of current psychosocial treatment efficacy and recommendations for future treatment development. Behavior Modification, 32, 267–301.

    Article  PubMed  PubMed Central  Google Scholar 

  • Goldstein, B. I., Carnethon, M. R., Matthews, K. A., McIntyre, R. S., Miller, G. E., Raghuveer, G., et al. (2015). Major depressive disorder and bipolar disorder predispose youth to accelerated atherosclerosis and early cardiovascular disease: A scientific statement from the American Heart Association. Circulation, 132, 965–986.

    Article  PubMed  Google Scholar 

  • Goldstein, B. I., Fagiolini, A., Houck, P., & Kupfer, D. (2009). Cardiovascular disease and hypertension among adults with bipolar disorder in the United States. Bipolar Disorders, 11, 657–662.

    Article  PubMed  PubMed Central  Google Scholar 

  • Goodrich, D. E., Kilbourne, A. M., Lai, Z., Post, E. P., Bowersox, N. W., Mezuk, B., et al. (2012). Design and rationale of a randomized controlled trial to reduce cardiovascular disease risk for patients with bipolar disorder. Contemporary Clinical Trials, 33, 666–678. https://doi.org/10.1016/j.cct.2012.02.010.

    Article  PubMed  Google Scholar 

  • Interian, A., Martinez, I. E., Guarnaccia, P. J., Vega, W. A., & Escobar, J. I. (2007). A qualitative analysis of the perception of stigma among Latinos receiving antidepressants. Psychiatric Services, 58, 1591–1594.

    Article  PubMed  Google Scholar 

  • Jeragh-Alhaddad, F. B., Waheedi, M., Barber, N. D., & Brock, T. P. (2015). Barriers to medication taking among Kuwaiti patients with type 2 diabetes: A qualitative study. Patient Preference and Adherence, 9, 1491–1503.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kamran, A., Sadeghieh, S., Biria, M., Malepour, A., & Heydan, H. (2014). Determinants of patient’s adherence to hypertension medications: Application of health belief model among rural patients. Annals of Medical and Health Sciences Research, 4, 922–927. https://doi.org/10.4103/2141-9248.144914.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Kendell, R. E. (2001). The distinction between mental and physical illness. The British Journal of Psychiatry: The Journal of Mental Science, 178, 490–493.

    Article  CAS  Google Scholar 

  • Kilbourne, A. M., Goodrich, D. E., O’Donnell, A. N., & Miller, C. J. (2012). Integrating bipolar disorder management in primary care. Current Psychiatry Reports, 14, 687–695. https://doi.org/10.1007/s11920-012-0325-4.

    Article  PubMed  PubMed Central  Google Scholar 

  • Krueger, R. (2002). Designing and conducting focus group interviewing. Minneapolis, MN: University of Minnesota. http://www.eiu.edu/ihec/Krueger-FocusGroupInterviews.pdf.

  • Lacro, J. P., Dunn, L. B., Dolder, C. R., & Jeste, D. V. (2002). Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: A comprehensive review of recent literature. Journal of Clinical Psychiatry, 63, 892–909.

    Article  PubMed  Google Scholar 

  • Lanouette, N., Folsom, D. P., Sciolla, A., & Jeste, D. V. (2009). Psychotropic medication nonadherence among United States Latinos: A comprehensive review of the literature. Psychiatric Services, 60, 157–174.

    Article  PubMed  Google Scholar 

  • Leclerc, E., Mansur, R. B., & Brietzke, E. (2013). Determinants of adherence to treatment in bipolar disorder: A comprehensive review. Journal of Affective Disorders, 149, 247–252.

    Article  PubMed  Google Scholar 

  • Levin, J. B., Tatsuoka, C., Cassidy, K. A., Aebi, M. E., & Sajatovic, M. (2015). Trajectories of medication attitudes and adherence behvior change in non-adherent bipolar patients. Comprehensive Psychiatry, 58, 29–36. https://doi.org/10.1016/j.comppsych.2014.11.023.

    Article  PubMed  Google Scholar 

  • Maina, G., Bechon, E., Rigardetto, S., & Salvi, V. (2013). General medical conditions are associated with delay to treatment in patients with bipolar disorder. Psychosomatics, 54, 437–442.

    Article  PubMed  Google Scholar 

  • Rodríguez-Gómez, J. R., & Salas, C. C. (2006). Treatment adherence in ethnic minorities: Particularities and alternatives. In W. T. O’Donohue (Ed.), Promoting treatment adherence: A practical handbook for health care providers (pp. 393–400). London: Sage Publications, Ltd.

    Chapter  Google Scholar 

  • Sajatovic, M., Ignacio, R. V., West, J. A., Cassidy, K. A., Safavi, R., Kilbourne, A. M., et al. (2009). Predictors of nonadherence among individuals with bipolar disorder receiving treatment in a community mental health clinic. Comprehensive Psychiatry, 50, 100–107.

    Article  PubMed  Google Scholar 

  • Samalin, L., Bellivier, F., Giordana, B., Yon, L., Milhiet, V., El-Hage, W., et al. (2014). Patients’ perspectives on residual symptoms in bipolar disorder: A focus group study. The Journal of Nervous and Mental Disease, 202, 550–555.

    Article  PubMed  Google Scholar 

  • Slomka, J. M., Piette, J. D., Post, E. P., Krein, S. L., Lai, Z., Goodrich, D. E., et al. (2012). Mood disorder symptoms and elevated cardiovascular disease risk in patients with bipolar disorder. Journal of Affective Disorders, 138, 405–408. https://doi.org/10.1016/j.jad.2012.01.005.

    Article  PubMed  PubMed Central  Google Scholar 

  • Vargas-Huicochea, L., Berlanga, C., & Fresán, A. (2014). Taking or not taking medications: Psychiatric treatment perceptions in patients diagnosed with bipolar disorder. Journal of Clinical Pharmacy and Therapeutics, 39, 673–679. https://doi.org/10.1111/jcpt.12210.

    Article  PubMed  CAS  Google Scholar 

  • Zhang, Y., & Wildemuth, M. (2009). Qualitative analysis of content. In B. Wildemuth (Ed.), Applications of social research methods to questions in information and library science (pp. 308–319). Westport, CT: Libraries Unlimited.

    Google Scholar 

Download references

Acknowledgements

Research reported in this publication was supported by the National Institute on Minority Health and Health Disparities of the National Institutes of Health Award Number #R25MD007607. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank Dr. Estela Estape for comments on the manuscript and Yashira Arroyo, MS for revision of the tables.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sandra I. Ralat.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ralat, S.I., Depp, C.A. & Bernal, G. Reasons for Nonadherence to Psychiatric Medication and Cardiovascular Risk Factors Treatment Among Latino Bipolar Disorder Patients Living in Puerto Rico: A Qualitative Study. Community Ment Health J 54, 707–716 (2018). https://doi.org/10.1007/s10597-017-0202-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10597-017-0202-z

Keywords

Navigation