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Synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines from 2-alkylaminobenzaldehydes

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Chemistry of Heterocyclic Compounds Aims and scope

A simple methodology was developed for the synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines by treatment of the respective 2-alkylaminobenzaldehydes with hydrogen chloride solution in dioxane at room temperature.

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Authors and Affiliations

  1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow, 117997, GSP-7, Russia

    Dmitry S. Ivanov, Elvira R. Zaitseva, Alexander Yu. Smirnov, Nadezhda S. Baleeva & Mikhail S. Baranov

  2. Pirogov Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, 1 Ostrovityanova St., Moscow, 117997, Russia

    Alexander Yu. Smirnov, Nadezhda S. Baleeva & Mikhail S. Baranov

Authors
  1. Dmitry S. Ivanov
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  2. Elvira R. Zaitseva
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  3. Alexander Yu. Smirnov
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  4. Nadezhda S. Baleeva
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  5. Mikhail S. Baranov
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Corresponding author

Correspondence to Alexander Yu. Smirnov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2022, 58(6/7), 354–357

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Ivanov, D.S., Zaitseva, E.R., Smirnov, A.Y. et al. Synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines from 2-alkylaminobenzaldehydes. Chem Heterocycl Comp 58, 354–357 (2022). https://doi.org/10.1007/s10593-022-03097-4

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  • DOI: https://doi.org/10.1007/s10593-022-03097-4

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