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2H-Azirines in medicinal chemistry

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Chemistry of Heterocyclic Compounds Aims and scope

The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

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This work was supported by the Grants Council of the President of the Russian Federation (grant MK-2698.2019.3).

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Authors and Affiliations

  1. Institute of Chemistry, Saint Petersburg State University, 7/9 University Embankment, Saint Petersburg, 199034, Russia

    Pavel А. Sakharov, Mikhail S. Novikov & Nikolai V. Rostovskii

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  1. Pavel А. Sakharov
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  2. Mikhail S. Novikov
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Correspondence to Nikolai V. Rostovskii.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2021, 57(5), 512–521

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Sakharov, P.А., Novikov, M.S. & Rostovskii, N.V. 2H-Azirines in medicinal chemistry. Chem Heterocycl Comp 57, 512–521 (2021). https://doi.org/10.1007/s10593-021-02934-2

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