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Synthesis of 5-(aminomethylidene)imidazol-4-ones by using N,N-dialkylformamide acetals

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Chemistry of Heterocyclic Compounds Aims and scope

We have developed a simple methodology for the synthesis of various 5-(aminomethylidene)imidazol-4-ones by condensation reactions of imidazol-4-one that was prepared in situ and acetals of N,N-dialkylformamides.

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This study received financial support from the Grants Council of the President of the Russian Federation (grant MK-1216.2019.3).

The authors would like to express their gratitude to Candidate of Chemical Sciences А. А. Tabolin (N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences) for recording IR spectra.

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Authors and Affiliations

  1. D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow, 125047, Russia

    Elvira R. Zaitseva

  2. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow, 117997, Russia

    Elvira R. Zaitseva, Alexander Yu. Smirnov, Igor A. Ivanov, Konstantin S. Mineev & Mikhail S. Baranov

  3. N. I. Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow, 117997, Russia

    Mikhail S. Baranov

Authors
  1. Elvira R. Zaitseva
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  2. Alexander Yu. Smirnov
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  3. Igor A. Ivanov
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  4. Konstantin S. Mineev
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  5. Mikhail S. Baranov
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Corresponding author

Correspondence to Alexander Yu. Smirnov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(8), 1097–1099

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Zaitseva, E.R., Smirnov, A.Y., Ivanov, I.A. et al. Synthesis of 5-(aminomethylidene)imidazol-4-ones by using N,N-dialkylformamide acetals. Chem Heterocycl Comp 56, 1097–1099 (2020). https://doi.org/10.1007/s10593-020-02779-1

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  • DOI: https://doi.org/10.1007/s10593-020-02779-1

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