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Electrophile-Induced Reactions of Cross-Conjugated Enynones in the Synthesis of Heterocycles

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Chemistry of Heterocyclic Compounds Aims and scope

Being compounds with multiple electrophilic centers, cross-conjugated enynones can be involved in various transformations upon treatment with electrophiles, in particular, Lewis and Brønsted acids, providing a convenient access to acyclic and cyclic compounds. This review covers literature data on electrophile-assisted reactions of substrates with cross-conjugated enynone scaffold toward the synthesis of heterocyclic compounds. The information is arranged according to the type of enynone motif, and chemical transformations of 2-(alkyn-1-yl)alk-2-en-1-ones and alk-1-en-4-yn-3-ones are discussed. The bibliography includes 52 sources.

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Authors and Affiliations

  1. Institute of Chemistry, Saint Petersburg State University, 26 Universitetsky Ave, Saint Petersburg, 198504, Russia

    Alena S. Pankova

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  1. Alena S. Pankova
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Correspondence to Alena S. Pankova.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(7), 829–836

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Pankova, A.S. Electrophile-Induced Reactions of Cross-Conjugated Enynones in the Synthesis of Heterocycles. Chem Heterocycl Comp 56, 829–836 (2020). https://doi.org/10.1007/s10593-020-02739-9

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  • DOI: https://doi.org/10.1007/s10593-020-02739-9

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