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Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity

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Chemistry of Heterocyclic Compounds Aims and scope

Several D-(+)-camphoric acid imides, not previously described in the literature, were synthesized with good yields. The synthesis of previously known imides was improved. The cytotoxicity and antiviral activity of all synthesized imides were studied.

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The authors would like to express their gratitude to the Collective Use Chemical Service Center of the Siberian Branch of Russian Academy of Sciences, for the obtained spectra and analytical data, as well as Dr. D. S. Fadeev for the obtained NMR spectra data. The authors also would like to thank Prof. J. Neyts, Dr. D. Jochmans, and C. Collard (Rega Institute for Medical Research, KU Leuven) for the obtained data on the antiviral activity.

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Authors and Affiliations

  1. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Akademika Lavrentieva Ave., Novosibirsk, 630090, Russia

    Vladimir V. Chernyshov, Olga I. Yarovaya & Nariman F. Salakhutdinov

  2. Novosibirsk State University, 2 Pirogova St., Novosibirsk, 630090, Russia

    Vladimir V. Chernyshov, Olga I. Yarovaya, Roman Yu. Peshkov & Nariman F. Salakhutdinov

Authors
  1. Vladimir V. Chernyshov
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  2. Olga I. Yarovaya
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  3. Roman Yu. Peshkov
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  4. Nariman F. Salakhutdinov
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Corresponding author

Correspondence to Vladimir V. Chernyshov.

Additional information

Supplementary information file containing 1H and 13C NMR spectra, IR spectra, and HRMS of all synthesized compounds is available at the journal website at http://link.springer.com/journal/10593.

Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(6), 763–768

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Chernyshov, V.V., Yarovaya, O.I., Peshkov, R.Y. et al. Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity. Chem Heterocycl Comp 56, 763–768 (2020). https://doi.org/10.1007/s10593-020-02728-y

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  • DOI: https://doi.org/10.1007/s10593-020-02728-y

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