By the action of acetic acid on 2-morpholinochromanes, a series of chroman-2-ols were obtained in which the hydroxyl group is easily substituted by a primary or secondary amine or benzyl carbamate fragments. In the case of hydrazines and hydrazides of carboxylic acids, the corresponding hydrazones are isolated.
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This study was supported by the Russian Science Foundation (grant 19-13-00421).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(3), 311–319
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Semenova, I.А., Korzhenko, K.S., Osipov, D.V. et al. Synthesis and reactions of chroman-2-ols and their benzo analogs with N-nucleophiles. Chem Heterocycl Comp 56, 311–319 (2020). https://doi.org/10.1007/s10593-020-02661-0
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DOI: https://doi.org/10.1007/s10593-020-02661-0