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An Expeditious Ultrasound-Initiated Green Synthesis of 1,2,4-Thiadiazoles in Water

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Chemistry of Heterocyclic Compounds Aims and scope

A convenient, environmentally benign, metal- and catalyst-free protocol has been developed for the conversion of thioamides to the corresponding 1,2,4-thiadiazole derivatives with chloranil under ultrasound irradiation in water at room temperature. This paper describes a general procedure for the synthesis of different 1,2,4-thiadiazoles in excellent yield in short reaction time via sonochemistry.

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Authors and Affiliations

  1. Department of Chemistry, Indian Institute of Technology, Banaras Hindu University, Varanasi, 221005, India

    Swati Chauhan, Pratibha Verma, Ankush Mishra & Vandana Srivastava

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  1. Swati Chauhan
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  2. Pratibha Verma
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  3. Ankush Mishra
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  4. Vandana Srivastava
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Correspondence to Vandana Srivastava.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(1), 123–126

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Chauhan, S., Verma, P., Mishra, A. et al. An Expeditious Ultrasound-Initiated Green Synthesis of 1,2,4-Thiadiazoles in Water. Chem Heterocycl Comp 56, 123–126 (2020). https://doi.org/10.1007/s10593-020-02632-5

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  • DOI: https://doi.org/10.1007/s10593-020-02632-5

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