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N-(Alkoxy)- and N-(acyloxy)phthalimides in organic synthesis: free radical synthetic approaches and applications (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

The microreview covers selected examples of the free radical cross-dehydrogenative C–O coupling of various CH reagents with N-hydroxyphthalimide leading to N-(alkoxy)- and N-(acyloxy)phthalimides. Synthetic applications of the latter associated with the cleavage of N–O bond leading to the O-, N- and C-centered free radicals are also reviewed.

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Acknowledgement

This work is supported by a grant from the President of the Russian Federation for state support of young Russian scientists (grant MK-3613.2019.3).

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russia

    Alexander S. Budnikov & Igor B. Krylov

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  1. Alexander S. Budnikov
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  2. Igor B. Krylov
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Correspondence to Igor B. Krylov.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(1), 36–38

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Budnikov, A.S., Krylov, I.B. N-(Alkoxy)- and N-(acyloxy)phthalimides in organic synthesis: free radical synthetic approaches and applications (microreview). Chem Heterocycl Comp 56, 36–38 (2020). https://doi.org/10.1007/s10593-020-02618-3

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  • DOI: https://doi.org/10.1007/s10593-020-02618-3

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