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One-Pot Three-Component Synthesis of Polysubstituted Tetrahydroindoles

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Chemistry of Heterocyclic Compounds Aims and scope

A series of novel fused pyrrole derivatives was synthesized by one-pot three-component reaction of β-enaminoketones, derived from cyclohexane-1,3-dione or dimedone, arylglyoxal hydrates, and 1,3-dimethylbarbituric acid in EtOH.

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Authors and Affiliations

  1. V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv, 61022, Ukraine

    Nataliia V. Chechina, Nadezhda N. Kolos & Irina V. Omelchenko

  2. State Scientific Institution “Institute for Single Crystals”, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv, 61001, Ukraine

    Irina V. Omelchenko

Authors
  1. Nataliia V. Chechina
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  2. Nadezhda N. Kolos
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  3. Irina V. Omelchenko
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Corresponding author

Correspondence to Nadezhda N. Kolos.

Additional information

Supplementary information file containing 1H and 13C NMR spectra of compounds 1a–o, 9a,b and mass spectrum of compound 1b is available at the journal website http://link.springer.com/journal/10593.

Published in Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(12), 1190–1196

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Chechina, N.V., Kolos, N.N. & Omelchenko, I.V. One-Pot Three-Component Synthesis of Polysubstituted Tetrahydroindoles. Chem Heterocycl Comp 55, 1190–1196 (2019). https://doi.org/10.1007/s10593-019-02600-8

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  • DOI: https://doi.org/10.1007/s10593-019-02600-8

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