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Three-Component Condensation of 4-Imino-1-Phenylimidazolidin-2-One with Aldehydes and Meldrum's Acid: Synthesis of Imidazo[4,5-b]Pyridine-2,5(4H,6H)-Diones and 5-Substituted 1-Phenylhydantoins

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Chemistry of Heterocyclic Compounds Aims and scope

A convenient method for the synthesis of previously unknown imidazo[4,5-b]pyridine-2,5(4H,6H)-diones has been developed, based on a three-component condensation of 4-imino-1-phenylimidazolidin-2-one with aldehydes and Meldrum's acid. The possibility of accessing 5-substituted 1-phenylhydantoins based on the acid hydrolysis of imidazo[4,5-b]pyridine-2,5(4H,6H)-diones was shown.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russia

    Constantine S. Krylov, Andrey N. Komogortsev, Boris V. Lichitsky, Artem N. Fakhrutdinov, Arkady А. Dudinov & Mikhail M. Krayushkin

Authors
  1. Constantine S. Krylov
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  2. Andrey N. Komogortsev
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  3. Boris V. Lichitsky
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  4. Artem N. Fakhrutdinov
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  5. Arkady А. Dudinov
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  6. Mikhail M. Krayushkin
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Correspondence to Andrey N. Komogortsev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(9), 851–855

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Krylov, C.S., Komogortsev, A.N., Lichitsky, B.V. et al. Three-Component Condensation of 4-Imino-1-Phenylimidazolidin-2-One with Aldehydes and Meldrum's Acid: Synthesis of Imidazo[4,5-b]Pyridine-2,5(4H,6H)-Diones and 5-Substituted 1-Phenylhydantoins. Chem Heterocycl Comp 55, 851–855 (2019). https://doi.org/10.1007/s10593-019-02548-9

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  • DOI: https://doi.org/10.1007/s10593-019-02548-9

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