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Chemistry of Heterocyclic Compounds

, Volume 55, Issue 4–5, pp 465–468 | Cite as

Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones by domino reactions of amino acids with ynones

  • Mariia Miliutina
  • Yevhen Ivon
  • Evgeniy Y. Slobodyanyuk
  • Syeda Abida Ejaz
  • Jamshed Iqbal
  • Alexander Villinger
  • Viktor O. Iaroshenko
  • Peter LangerEmail author
Article
  • 25 Downloads

The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic α,β-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.

Keywords

amino acids chromeno[2,3-c]pyrrol-9(2H)-ones heterocycles alkaline phosphatase inhibitory activity domino reactions 

Supplementary material

10593_2019_2481_MOESM1_ESM.pdf (1.9 mb)
ESM 1 (PDF 1894 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Mariia Miliutina
    • 1
  • Yevhen Ivon
    • 1
    • 2
  • Evgeniy Y. Slobodyanyuk
    • 1
    • 2
  • Syeda Abida Ejaz
    • 3
  • Jamshed Iqbal
    • 3
  • Alexander Villinger
    • 1
  • Viktor O. Iaroshenko
    • 1
    • 4
  • Peter Langer
    • 1
    • 5
    Email author
  1. 1.Institut für ChemieUniversität RostockRostockGermany
  2. 2.Taras Shevchenko National University of KyivKyivUkraine
  3. 3.Centre for Advanced Drug ResearchCOMSATS Institute of Information TechnologyAbbottabadPakistan
  4. 4.Centre of Molecular and Macromolecular StudiesLodzPoland
  5. 5.Leibniz Institut für Katalyse e. V. an der Universität RostockRostockGermany

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