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Synthesis of novel spiro-condensed 2-amino-4H-pyrans based on 1,2-benzoxathiin-4(3H)-one 2,2-dioxide

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Chemistry of Heterocyclic Compounds Aims and scope

A series of new spiro-condensed 2-amino-4H-pyrans were synthesized by three-component interaction of 1,2-benzoxathiin-4(3H)-one 2,2-dioxide, malononitrile, and cyclic carbonyls in moderate to high yields. This is one of the first examples of 1,2-benzoxathiin-4(3H)-one 2,2-dioxide application in multicomponent transformations.

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Authors and Affiliations

  1. National University of Pharmacy, 53 Pushkinska St., Kharkiv, 61002, Ukraine

    Galina V. Grygoriv, Dmitry A. Lega, Valentine P. Chernykh & Leonid A. Shemchuk

  2. Deparment of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, 6 Grunwaldzka St., 60-780, Poznan, Poland

    Lucjusz Zaprutko, Andrzej K. Gzella & Ewa Wieczorek-Dziurla

Authors
  1. Galina V. Grygoriv
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  2. Dmitry A. Lega
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  3. Lucjusz Zaprutko
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  4. Andrzej K. Gzella
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  5. Ewa Wieczorek-Dziurla
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  6. Valentine P. Chernykh
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  7. Leonid A. Shemchuk
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Corresponding author

Correspondence to Leonid A. Shemchuk.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(3), 254–260

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Grygoriv, G.V., Lega, D.A., Zaprutko, L. et al. Synthesis of novel spiro-condensed 2-amino-4H-pyrans based on 1,2-benzoxathiin-4(3H)-one 2,2-dioxide. Chem Heterocycl Comp 55, 254–260 (2019). https://doi.org/10.1007/s10593-019-02450-4

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  • DOI: https://doi.org/10.1007/s10593-019-02450-4

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