Synthesis of 5-hydroxyfuran-2(5H)-one derivatives (microreview)

In this microreview, we describe methods for the synthesis of 5-hydroxyfuran-2(5H)-one derivatives, which have been published over the last 5 years. The main routes for the preparation of 5-hydroxyfuran-2(5H)-one derivatives include transformations of 2-oxocarboxylic acids, formylation or carboxylation of functionalized aromatic (heterocyclic) compounds, as well as synthetic modifications of furan derivatives.

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This work was financed by a grant from the President of the Russian Federation for support of young scientists in Russia (MK-5982.2018.3).

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Correspondence to Sergey V. Fedoseev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(8), 795–761

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Fedoseev, S.V., Belikov, M.Y. Synthesis of 5-hydroxyfuran-2(5H)-one derivatives (microreview). Chem Heterocycl Comp 54, 759–761 (2018). https://doi.org/10.1007/s10593-018-2345-4

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Keywords

  • Microreview
  • Pharmacy