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ZnO nanorod-catalyzed three-component reaction of euparin, aldehyde, and dialkyl acetylenedicarboxylate: green synthesis of chromene derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

New chromene derivatives, 9H-furo[2,3-f]chromene-7,8-dicarboxylates, have been synthesized in high yields by a three-component reaction of euparin (isolated from Petasites hybridus), an aldehyde, and dialkyl acetylenedicarboxylate in the presence of PPh3 and catalytic amount of ZnO nanorods under solvent-free conditions at room temperature. ZnO nanorods showed a strong effect on improving the yield of the desired products. Chromene derivatives can be easily separated from the reaction mixture in a simple work-up, and the catalyst may be recovered and reused without considerable loss of activity.

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Authors and Affiliations

  1. Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh, Iran

    Fatemeh Sheikholeslami-Farahani

  2. Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

    Hossein Karami, Masoomeh Salimifard, Saeid Afshari Sharif Abad & Ali Akbar Eslami

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  1. Fatemeh Sheikholeslami-Farahani
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  2. Hossein Karami
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  3. Masoomeh Salimifard
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  4. Saeid Afshari Sharif Abad
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  5. Ali Akbar Eslami
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Correspondence to Fatemeh Sheikholeslami-Farahani.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(6), 593–597

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Sheikholeslami-Farahani, F., Karami, H., Salimifard, M. et al. ZnO nanorod-catalyzed three-component reaction of euparin, aldehyde, and dialkyl acetylenedicarboxylate: green synthesis of chromene derivatives. Chem Heterocycl Comp 54, 593–597 (2018). https://doi.org/10.1007/s10593-018-2313-z

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  • DOI: https://doi.org/10.1007/s10593-018-2313-z

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