Chemistry of Heterocyclic Compounds

, Volume 54, Issue 4, pp 400–402 | Cite as

Open image in new window Use of azetidine scaffolds in stereoselective transformations (microreview)

  • Renzo Luisi
  • Leonardo Degennaro

Open image in new window Noteworthy stereoselective approaches toward the synthesis of densely substituted azetidines are reported. This microreview covers a selection of the latest efficient methods for the functionalization of azetidine cores by metalation, C–H activation, radical or biocatalytic processes, as well as nonclassical and large-scale preparative procedures.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Pharmacy – Pharmaceutical SciencesUniversity of Bari Aldo Moro, FLAME-Lab – Flow Chemistry and Microreactor Technology LaboratoryBariItaly

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