Chemistry of Heterocyclic Compounds

, Volume 54, Issue 4, pp 400–402 | Cite as

Open image in new window Use of azetidine scaffolds in stereoselective transformations (microreview)


Open image in new window Noteworthy stereoselective approaches toward the synthesis of densely substituted azetidines are reported. This microreview covers a selection of the latest efficient methods for the functionalization of azetidine cores by metalation, C–H activation, radical or biocatalytic processes, as well as nonclassical and large-scale preparative procedures.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Pharmacy – Pharmaceutical SciencesUniversity of Bari Aldo Moro, FLAME-Lab – Flow Chemistry and Microreactor Technology LaboratoryBariItaly

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