Chemistry of Heterocyclic Compounds

, Volume 54, Issue 4, pp 394–396 | Cite as

Open image in new window 4-Hydroxycoumarins as Michael donors in asymmetric routes to polycyclic coumarins (microreview)

  • Mariagrazia Rullo
  • Leonardo Pisani

Different [3,4]-fused polycyclic 2H-chromen-2-ones can be prepared in a stereoselective fashion starting from 4-hydroxycoumarins as nucleophilic synthones. Herein we report a brief overview of the most recent methods including Pd-catalyzed [3+3] annulation processes, organocatalytic one-pot and domino Michael addition/cyclization, tandem conjugate addition/hydroxyalkylation, and organocascade catalytic reaction.


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Authors and Affiliations

  1. 1.Department of Pharmacy – Pharmaceutical SciencesUniversity of Bari Aldo MoroBariItaly

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