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Copper(II) bromide-catalyzed conjugate addition of furans to α,β-unsaturated carbonyl compounds

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Chemistry of Heterocyclic Compounds Aims and scope

A simple method for the synthesis of 2-(3-oxoalkyl)furan derivatives based on conjugate addition of 2-substituted furans to various α,β-unsaturated carbonyl compounds in the presence of copper(II) bromide as catalyst was developed.

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This work was supported by the Russian Foundation for Basic Research (grant 16-33-00101 mol_a) and the Ministry of Education and Science of the Russian Federation (contract No. 02.a03.0008).

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Authors and Affiliations

  1. Perm State National Research University, 15 Bukirev St., Perm, 614990, Russia

    Alexander A. Fadeev, Maxim G. Uchuskin & Anton S. Makarov

  2. RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russia

    Maxim G. Uchuskin & Igor V. Trushkov

  3. Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela St., Moscow, 117997, Russia

    Igor V. Trushkov

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  1. Alexander A. Fadeev
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  2. Maxim G. Uchuskin
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  4. Anton S. Makarov
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Correspondence to Anton S. Makarov.

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A Supporting information file containing 1Н and 13С NMR spectra of all synthesized compounds is available at the journal website at http://link.springer.com/journal/10593.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(12), 1286–1293

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Fadeev, A.A., Uchuskin, M.G., Trushkov, I.V. et al. Copper(II) bromide-catalyzed conjugate addition of furans to α,β-unsaturated carbonyl compounds. Chem Heterocycl Comp 53, 1286–1293 (2017). https://doi.org/10.1007/s10593-018-2206-1

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  • DOI: https://doi.org/10.1007/s10593-018-2206-1

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