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Synthesis of monosubstituted 1,2,4,5-tetrazines – 3-amino-1,2,4,5-tetrazines

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Chemistry of Heterocyclic Compounds Aims and scope

The substitution of pyrazolyl moiety in 3-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine with N-nucleophiles provided a series of highnitrogen tetrazine derivatives, including 2-nitro-1-(1,2,4,5-tetrazin-3-yl)guanidine, N-(1H-tetrazol-5-yl)-1,2,4,5-tetrazin-3-amine, N-(1,2,4,5-tetrazin-3-yl)-1,2,4,5-tetrazin-3-amine, N,N'-di(1,2,4,5-tetrazin-3-yl)-1,2,4,5-tetrazine-3,6-diamine, N-(1,2,4,5-tetrazin-3-yl)-[1, 2, 4]triazolo[4,3-b][1, 2, 4, 5]tetrazin-6-amine, and tritetrazinylamine. The thermal stability of these new compounds was evaluated by differential scanning calorimetry and their energetic characteristics were calculated.

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  1. D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow, 125047, Russia

    Gennady F. Rudakov, Yurii A. Moiseenko & Natal’ya А. Spesivtseva

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  1. Gennady F. Rudakov
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  2. Yurii A. Moiseenko
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  3. Natal’ya А. Spesivtseva
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Correspondence to Gennady F. Rudakov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(6/7), 802–810

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Rudakov, G.F., Moiseenko, Y.A. & Spesivtseva, N.А. Synthesis of monosubstituted 1,2,4,5-tetrazines – 3-amino-1,2,4,5-tetrazines. Chem Heterocycl Comp 53, 802–810 (2017). https://doi.org/10.1007/s10593-017-2127-4

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