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Synthesis of seven-membered nitrogen heterocycles through the Ugi multicomponent reaction

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Chemistry of Heterocyclic Compounds Aims and scope

This paper reviews all the syntheses of 7-membered nitrogen heterocycles that are based on the Ugi multicomponent reaction. Different systems may be obtained in a diversity-oriented manner employing three general strategies: i) intramolecular Ugi reaction; ii) Ugi reaction followed by cyclization involving one additional functional group; iii) Ugi reaction followed by cyclization involving two additional functional groups.

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  1. Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso 31, 16146, Genova, Italy

    Luca Banfi, Andrea Basso, Chiara Lambruschini, Lisa Moni & Renata Riva

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  1. Luca Banfi
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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(4), 382–408

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Banfi, L., Basso, A., Lambruschini, C. et al. Synthesis of seven-membered nitrogen heterocycles through the Ugi multicomponent reaction. Chem Heterocycl Comp 53, 382–408 (2017). https://doi.org/10.1007/s10593-017-2065-1

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