Chemistry of Heterocyclic Compounds

, Volume 53, Issue 3, pp 240–255 | Cite as

N-(Hetero)aryl-2-imidazolines: an emerging privileged motif for contemporary drug design

REVIEWS

The diverse biological activities of compounds containing N-(hetero)aryl-2-imidazoline moiety and methods to construct them are comprehensively reviewed for the first time. This intriguing non-flat, cyclic amidine motif clearly represents an emerging privileged structure.

Keywords

cyclodehydration imidazoline N-arylation lead-like compounds privileged structures 

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© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Institute of ChemistrySaint Petersburg State UniversityPetrodvoretsRussia

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