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Fe3O4 nanoparticles as an efficient and reusable catalyst for the solvent-free synthesis of 1H-indole and 1H-pyrrole derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Magnetic Fe3O4 nanoparticles as a heterogeneous catalyst were found to be efficient for the synthesis of a series of pyrrole and indole derivatives using three-component reactions of primary amines, 1,3-dicarbonyl compounds, and activated acetylenic compounds under solvent-free conditions at room temperature. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification, and affordability of the catalyst.

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Authors and Affiliations

  1. Department of Chemistry, Qaemshahr Branch, Islamic Azad University, P.O. Box 163, Qaemshahr, Iran

    Seyyed Ebrahim Babaei, Zinatossadat Hossaini & Reza Ramezani Besheli

  2. Department of Chemistry, South of Tehran Branch, Islamic Azad University, P.O. Box 11, Tehran, Iran

    Vahid Tavakkoli

Authors
  1. Seyyed Ebrahim Babaei
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  2. Zinatossadat Hossaini
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  3. Reza Ramezani Besheli
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  4. Vahid Tavakkoli
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Corresponding author

Correspondence to Zinatossadat Hossaini.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(5), 294–298

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Babaei, S.E., Hossaini, Z., Besheli, R.R. et al. Fe3O4 nanoparticles as an efficient and reusable catalyst for the solvent-free synthesis of 1H-indole and 1H-pyrrole derivatives. Chem Heterocycl Comp 52, 294–298 (2016). https://doi.org/10.1007/s10593-016-1880-0

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  • DOI: https://doi.org/10.1007/s10593-016-1880-0

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