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The Fischer Reaction in the Synthesis of 2,3-Disubstituted 7-Azaindoles*

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Chemistry of Heterocyclic Compounds Aims and scope

We present the results of our study towards the synthesis of 2,3-disubstituted 7-azaindoles by cyclization of 2-pyridylhydrazones of aliphatic and alkylaromatic ketones under the conditions of Fischer reaction, catalyzed by polyphosphoric acid.

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This work received financial support from the Russian Foundation for Basic Research (grant 14-03-31289).

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Authors and Affiliations

  1. Moscow M. V. Lomonosov State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russia

    R. S. Alekseyev, E. V. Kabanova & V. I. Terenin

  2. Moscow M. V. Lomonosov State University, Baku Branch, 1 Universitetskaya St., Khojasan, Binagadi, Baku, AZ 1144, Azerbaijan

    S. R. Amirova

Authors
  1. R. S. Alekseyev
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  2. S. R. Amirova
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  3. E. V. Kabanova
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  4. V. I. Terenin
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Correspondence to R. S. Alekseyev.

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*Dedicated to Academician of the Russian Academy of Sciences Yu. N. Bubnov on the occasion of his 80th birthday.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1416-1427, September, 2014.

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Alekseyev, R.S., Amirova, S.R., Kabanova, E.V. et al. The Fischer Reaction in the Synthesis of 2,3-Disubstituted 7-Azaindoles*. Chem Heterocycl Comp 50, 1305–1315 (2014). https://doi.org/10.1007/s10593-014-1593-1

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  • DOI: https://doi.org/10.1007/s10593-014-1593-1

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