Chemistry of Heterocyclic Compounds

, Volume 48, Issue 8, pp 1228–1234 | Cite as

Reaction of 4,6-Dichloro-5-nitrobenzofuroxan with aromatic amines and nitrogen-containing heterocycles

  • E. M. Gibadullina
  • E. A. Chugunova
  • E. V. Mironova
  • D. B. Krivolapov
  • A. R. Burilov
  • L. M. Yusupova
  • M. A. Pudovik
Article

4,6-Dichloro-5-nitrobenzofuroxan reacts with aromatic and heterocyclic amines via the chlorine atom at the position 4 of the aromatic ring to give monоsubstitution products. In a similar reaction with piperazine, both amino groups undergo arylation to give a compound containing two benzofuroxan fragments.

Keywords

Benzofuroxan amination aromatic ring arylation monosubstitution 

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • E. M. Gibadullina
    • 1
  • E. A. Chugunova
    • 1
  • E. V. Mironova
    • 1
  • D. B. Krivolapov
    • 1
  • A. R. Burilov
    • 1
  • L. M. Yusupova
    • 2
  • M. A. Pudovik
    • 1
  1. 1.A. E. Arbuzov Institute of Organic and Physical ChemistryKazan Science Center, Russian Academy of SciencesKazanˈRussia
  2. 2.Kazan National Research Technological UniversityKazanˈRussia

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