Skip to main content
SpringerLink
Log in

Synthesis and reactions of some new selenolo[2,3-c]pyridazines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

New series of selenolo[2,3-c]pyridazine and pyrimido[4',5':4,5]selenolo[2,3-c]pyridazine derivatives were prepared from 4-cyano-5,6-diphenylpyridazine-3(2H)-selenone. Elemental analysis, IR, 1H NMR, and mass spectra confirmed the structures of the newly synthesized compounds.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. Hill, Eur. J. Clin. Nutr., 56, Suppl. 1, S36 (2002).

    Article  Google Scholar 

  2. M. A. Moyad, Urology, 59, 9 (2002).

    Article  Google Scholar 

  3. J. E. Spallholz, Bull. Selenium-Tellurium, No. 05, 1 (2001).

  4. J. E. Spallholz, Bull. Selenium-Tellurium, No. 10, 1 (2001).

  5. G. Mugesh, W.-W. Du Mont, and H. Sies, Chem. Rev., 101, 2125 (2001).

    Article  CAS  Google Scholar 

  6. M. S. Alaejos, F. J. Diaz Romero, and C. Diaz Romero, Nutrition, 16, 376 (2000).

    Article  CAS  Google Scholar 

  7. V. P. Litvinov and V. D. Dyachenko, Usp. Khim., 66, 1025 (1997).

    CAS  Google Scholar 

  8. Zh. I. Abramova and Z. Kh. Chernyi, in: N. V. Lazarev and I. D. Gadaskina (editors), Hazardous substances in industry, Vol. 3, Khimiya, Leningrad, 1977, p. 75.

    Google Scholar 

  9. K. E. Panter, W. J. Hartley, L. F. James, H. F. Mayland, B. L. Stegelmeier, and P. O. Kechele, Toxicol. Sci., 32, 217 (1996).

    Article  CAS  Google Scholar 

  10. R. Bohm, Pharmazie, 42, 793 (1987).

    CAS  Google Scholar 

  11. M. Koketsu, K. Tanaka, Y. Takenaka, C. D. Kwong, and H. Ishihara, Eur. J. Pharm. Sci., 15, 307 (2002).

    Article  CAS  Google Scholar 

  12. T. Wirth, Tetrahedron, 55, 1 (1999).

    Article  CAS  Google Scholar 

  13. N. Petragnani, H. A. Stefani, and C. J. Valduga, Tetrahedron, 57, 1411 (2001).

    Article  CAS  Google Scholar 

  14. S. Uemura, Chem. Ind., 40, 106 (1987).

    Google Scholar 

  15. A. Dari, L. E. Christiaens, and M. J. Renson, Acta Chem. Scand., 47, 208 (1993).

    Article  CAS  Google Scholar 

  16. V. Yu. Mortikov, V. P. Litvinov, A. M. Shestopalov, Yu. A. Sharanin, E. E. Apenova, G. A. Galegov, I. I. Abdullaev, and F. I. Abdullaev, Khim.-farm. Zh., 25, № 5, 41 (1991).

    CAS  Google Scholar 

  17. Yu. A. Sharanin, A. M. Shestopalov, G.. I. Khoroshilov, and V. D. Dyachenko, in: Abstracts of Reports at the All-Union Meeting "Natural Sciences for the National Economy", Perm, 1988, p. 126.

  18. A. M. Shestopalov, Yu. A. Sharanin, A. S. Demerkov, and L. A. Rodinovskaya, in: Abstracts of Reports at the All-Union Meeting "Natural Sciences for the National Economy", Perm, 1988, p. 126.

  19. Yu. N. Klimochkin, I. L. Moiseev, O. V. Abramov, G. V. Vladyko, L. V. Korobchenko, and E. I. Boreiko, Khim.-farm. Zh., 25, № 7, 49 (1991).

    CAS  Google Scholar 

  20. J. Młochowski, K. Klos, L. Syper, A. Dubowska-Inglot, and J. Zielińska-Jenczylik, Pol. Pat. 159 930; Ref. Zh. Khim., 17O67P (1994).

  21. S. El-Bahaic, M. G. Assy, and M. M. Hassanier, Pharmazie, 45, 791 (1990).

    Google Scholar 

  22. J. R. Hwu, L. L. Lai, G. H. Hakimelahi, and H. Davari, Helv. Chim. Acta, 77, 1037 (1994).

    Article  CAS  Google Scholar 

  23. B. E.-S. Bayomy, J. Serb. Chem. Soc., 55, 205 (1990).

    Google Scholar 

  24. H. Ishihara, M. Koketsu, Y. Fukuta, and F. Nada, J. Am. Chem. Soc., 123, 8408 (2001).

    Article  CAS  Google Scholar 

  25. K. D. Berlin, M. D. Thompson, B. J. Scherlag, and G. S. Smith, US Pat. 4 778 892; Ref. Zh. Khim., 14O108P (1989).

  26. A. M. Shestopalov, Yu. A. Sharanin, L. A. Rodinovskaya, V. Yu. Mortikov, V. P. Litvinov, and V. K. Promonenkov, in: Abstracts of Reports at the All-Union Conference "The Chemistry and Technology of Pyridine-Containing Pesticides", Chernogolovka, 1988, p. 122.

  27. L. Yu. Kuleshova, A. P. Burtnev, L. R. Kubasova, and G. V. Bergovykh, in: Topical Problems of the Pharmacy of the Non-Black Earth Zone. Collected Proceedings of the Ryazan Medical Institute, Ryazan, 1987, Vol. 92, p. 149.

  28. N. A. Platonova, Z. F. Gromova, and L. G. Breeva, in: Topical Problems of the Pharmacy of the Non- Black Earth Zone. Collected Proceedings of the Ryazan Medical Institute, Ryazan, 1987, Vol. 92, p. 53.

  29. G. Heinisch and H. Kopelent-Frank, in: Progress in Medicinal Chemistry, G. P. Ellis, G. B. West (editors), 1990, Vol. 27, p. 141.

  30. G. Heinisch and H. Kopelent-Frank, in: G. P. Ellis, G. B. West (editors), Progress in Medicinal Chemistry, 1990, Vol. 27, p. 1.

  31. F. M. Abdelrazek, P. Metz, and E. K. Farrag, Arch. Pharm., 337, 482 (2004).

    Article  CAS  Google Scholar 

  32. F. M. Abdelrazek, P. Metz, N. H. Metwally, and S. F. El-Mahrouky, Arch. Pharm., 339, 456 (2006).

    Article  CAS  Google Scholar 

  33. F. M. Abdelrazek, P. Metz, O. Kataeva, A. Jaeger, and S. F. El-Mahrouky, Arch. Pharm., 340, 543 (2007).

    Article  CAS  Google Scholar 

  34. Sh. H. Abdel-Hafez and M. A. Hussein, Arch. Pharm., 341, 240 (2008).

    Article  CAS  Google Scholar 

  35. F. M. Abdelrazek, N. H. Metwally, N. A. Kassab, and N. A. Sobhy, J. Heterocycl. Chem., 46, 1380 (2009).

    Article  CAS  Google Scholar 

  36. S. H. Abdel-Hafez, Russ. J. Bioorg. Chem., 36, 370 (2010).

    Article  CAS  Google Scholar 

  37. F. M. Abdelrazek, N. H. Metwally, N. A. Kassab, N. A.Sobhy, P. Metz, and A. Jaeger, J. Heterocycl. Chem., 47, 384 (2010).

    CAS  Google Scholar 

  38. Sh. H. Abdel-Hafez, Eur. J. Med. Chem., 43, 1971 (2008)

    Article  CAS  Google Scholar 

  39. J. P. Schaefer and J. Bloomfield, Org. Reactions, 15, 1 (1967).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Assiut University, Assuit, 71516, Egypt

    S. H. Abdel-Hafez, M. I. Abdel-Monem, M. G. Mohamed & S. A. M. Metwally

  2. Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt

    F. M. Abdelrazek

Authors
  1. S. H. Abdel-Hafez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. I. Abdel-Monem
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. G. Mohamed
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. F. M. Abdelrazek
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. A. M. Metwally
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to F. M. Abdelrazek.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 441–449, March, 2011.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Abdel-Hafez, S.H., Abdel-Monem, M.I., Mohamed, M.G. et al. Synthesis and reactions of some new selenolo[2,3-c]pyridazines. Chem Heterocycl Comp 47, 363–370 (2011). https://doi.org/10.1007/s10593-011-0765-5

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10593-011-0765-5

Keywords

Search

Navigation