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Synthesis of 2-(3-coumarinyl)pyrrolo[2,1-a]isoquinoline derivatives by the chichibabin reaction

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Chemistry of Heterocyclic Compounds Aims and scope

2-(3-Coumarinyl)-5,5-dimethyl-5,6-dihydropyrrolo[2,1-a]isoquinolines were synthesized by the Chichibabin reaction of 3,3-dimethyl-1,2,3,4-tetrahydroisoquinoline with 3-bromoacetylcoumarin. Derivatives of benzo[f]isoquinoline and benzo[f]coumarin were obtained similarly.

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References

  1. K. V. Vatsuro and G. L. Mishchenko, Named Reactions in Organic Chemistry [in Russian], Khimiya, Moscow (1976), p. 474.

    Google Scholar 

  2. A. G. Mikhailovskii and V. S. Shklyaev, Khim. Geterotsikl. Soedin., 291 (1997). [Chem. Heterocycl. Comp., 33, 243 (1997)].

    Google Scholar 

  3. N. N. Polygalova, A. G. Mikhailovskii, E. V. Vikhareva, and M. I. Vakhrin, Khim. Geterotsikl. Soedin., 1068 (2007). [Chem. Heterocycl. Comp., 43, 900 (2007)].

    Google Scholar 

  4. E. Pretsch, P. Bullman, and C. Affolter, Structure Determination of Organic Compounds [Russian translation], Mir, Moscow (2006), p. 201.

    Google Scholar 

  5. V. S. Shklyaev, B. B. Aleksandrov, G. I. Legotkina, M. I. Vakhrin, M. S. Gavrilov, and A. G. Mikhailovskii, Khim. Geterotsikl. Soedin., 1560 (1983). [Chem. Heterocycl. Comp., 19, 1242 (1983)].

    Google Scholar 

  6. B. B. Aleksandrov, V. S. Shklyaev, and Yu. V. Shklyaev, Khim. Geterotsikl. Soedin., 854 (1991). [Chem. Heterocycl. Comp., 27, 677 (1991)].

    Google Scholar 

  7. V. S. Shklyaev, B. B. Aleksandrov, A. G. Mikhailovskii, and M. I. Vakhrin, Khim. Geterotsikl. Soedin., 1239 (1989). [Chem. Heterocycl. Comp., 25, 1038 (1989)].

    Google Scholar 

  8. C. F. Koelsch, J. Am. Chem. Soc., 72, 2993 (1950).

    Article  CAS  Google Scholar 

  9. C. Moustapha, N. A. Abdel-Riheem, and A. O. Abdelhamid, Synth. Commun., 35, 249 (2005).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, 2 Polevaya St., Perm, 614990, Russia

    Yu. A. Kulikova, O. V. Surikova, A. G. Mikhailovskii & M. I. Vakhrin

Authors
  1. Yu. A. Kulikova
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  2. O. V. Surikova
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  3. A. G. Mikhailovskii
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  4. M. I. Vakhrin
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Corresponding author

Correspondence to A. G. Mikhailovskii.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 357–361, March, 2011.

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Kulikova, Y.A., Surikova, O.V., Mikhailovskii, A.G. et al. Synthesis of 2-(3-coumarinyl)pyrrolo[2,1-a]isoquinoline derivatives by the chichibabin reaction. Chem Heterocycl Comp 47, 290–293 (2011). https://doi.org/10.1007/s10593-011-0755-7

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  • DOI: https://doi.org/10.1007/s10593-011-0755-7

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