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Regioselective N-arylation of nitroazoles. Determination of the structure of N-arylnitro-azoles on the basis of NMR spectroscopic data and quantum-chemical calculations

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Chemistry of Heterocyclic Compounds Aims and scope

The N-arylation of a series of nitroazoles has been studied with the aid of diaryliodonium salts in the presence of CuI under the action of microwave radiation. It was found that alkylation proceeds regioselectively in each actual case with the formation of one of two possible isomers. The correct structure of the N-arylation products was established on the basis of NMR spectroscopy.

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Authors and Affiliations

  1. Moscow M. V. Lomonosov State University, Faculty of Chemistry, Moscow, 119991, GSP-1, Leninskie Gory, 1–3, Russia

    V. A. Chertkov & D. V. Davydov

  2. Russian Federation State Science Center, State Research Institute of Chemistry and Technology of Organoelement Compounds, 38 Shosse Entuziastov, Moscow, 111123, Russia

    A. K. Shestakova

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  1. V. A. Chertkov
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  2. A. K. Shestakova
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  3. D. V. Davydov
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Correspondence to V. A. Chertkov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 63–74, January, 2011.

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Chertkov, V.A., Shestakova, A.K. & Davydov, D.V. Regioselective N-arylation of nitroazoles. Determination of the structure of N-arylnitro-azoles on the basis of NMR spectroscopic data and quantum-chemical calculations. Chem Heterocycl Comp 47, 45–54 (2011). https://doi.org/10.1007/s10593-011-0718-z

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