Skip to main content
Log in

NitropyridineS. 9*. Synthesis of substituted 3-amino-5-nitropyridines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Substituted 3-amino-5-nitropyridines have been synthesized by the Curtius, Schmidt, and Hofmann reactions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. G. P. Sagitullina, A. K. Garkushenko, L. V. Glizdinskaya, N. V. Poendaev, D. E. Eremeeva, and R. S. Sagitullin, Khim. Geterotsikl. Soed., 699 (2010). [Chem. Heterocycl. Comp., 46, 553 (2010)].

    Google Scholar 

  2. G. Mosher, in: R. Elderfield (editor), Heterocyclic Compounds [Russian translation], Izd-vo Inostr. Lit., Moscow, 1953, Vol. 1, p 432.

    Google Scholar 

  3. V. L. Rusinov, and O. N. Chupakhin, Nitroazines [in Russian], Nauka, Novosibirsk, 1991, p. 10.

    Google Scholar 

  4. E. Plazek and L. Kuczynski, Zesz. Nauk. Politechn. wrocl., 4, 17 (1954).

    Google Scholar 

  5. M. Kimura and Y. Takano, J. Pharm. Soc. Jpn., 79, 549 (1959).

    CAS  Google Scholar 

  6. M. Nakadate, Y. Takano, T. Hirayama, S. Sakaizawa, T. Hirano, K. Okamoto, K. Hirao, T. Kawamura, and M. Kimura, Chem. Pharm, Bull., 13, 113 (1965).

    CAS  Google Scholar 

  7. P. Tomasik and E. Plazek, Rozn. Chem., 38, 709 (1964).

    CAS  Google Scholar 

  8. F. A. French and E. J. Blanz, J. Med. Chem., 17, 172 (1974).

    Article  CAS  Google Scholar 

  9. P. Tomasik and W. Grzeniek, Rozn. Chem., 43, 569 (1969).

    CAS  Google Scholar 

  10. G. P. Sagitullina, A. K. Garkushenko, E. G. Atavin, and R. S. Sagitullin, Mendeleev Commun., 19, 155 (2009).

    Article  CAS  Google Scholar 

  11. G. P. Sagitullina, A. K. Garkushenko, and R. S. Sagitullin, Khim. Geterotsikl. Soed., 1430 (2009). [Chem. Heterocycl. Comp., 45, 1147 (2009)].

    Google Scholar 

  12. E. S. Willis and D. F. Len, Organic Reactions [Russian translation], Izd-vo Inostr. Lit., Moscow, 1951, Vol. 3, p. 255.

    Google Scholar 

  13. P. Radlick and L. R. Brown, Synthesis, 290 (1974).

  14. B. K. Swaminathan and N. Venkatasubramanian, J. Chem. Soc., Perkin Trans 2, 1161 (1975).

    Google Scholar 

  15. A. S. Radhakrishna, M. E. Parham, R. M. Riggs, and G. M. Loudon, J. Org. Chem., 44, 1746 (1979).

    Article  CAS  Google Scholar 

  16. X. Huang. M. Seid, and J. W. Keillor, J. Org. Chem., 62, 7495 (1997).

    Article  CAS  Google Scholar 

  17. H. Togo, T. Nabana, and K. Yamaguchi, J. Org. Chem., 65, 8391 (2000).

    Article  CAS  Google Scholar 

  18. C. Yu, Y. Jiang, B. Liu, and L. Hu, Tetrahedron Lett., 42, 1449 (2001).

    Article  CAS  Google Scholar 

  19. M. Jure and I. Jaunzeme, Latv. J. Chem., No. 4, 3 (2000).

  20. T. Shioiri, K. Ninomiya, and S. Yamada, J. Am. Chem. Soc., 94, 6203 (1972).

    Article  CAS  Google Scholar 

  21. S. Yamada, Y. Kasai, T. Shioiri, Tetrahedron. Lett., 14, 1595 (1973).

    Article  Google Scholar 

  22. K. Ninomiya, T. Shioiri, and S. Yamada, Tetrahedron, 30, 2151 (1974).

    Article  CAS  Google Scholar 

  23. J. R. Damewood, Jr., P. D. Edwards, S. Feeney, B. C. Gomes, G. B. Steelman, P. A. Tuthill, J. C. Williams, P. Warner, S. A. Woolson, D. J. Wolanin, and C. A. Veale, J. Med. Chem., 37, 3303 (1994).

    Article  CAS  Google Scholar 

  24. G. C. G. Pais and M. E. Maier, J. Org. Chem., 64, 4551 (1999).

    Article  CAS  Google Scholar 

  25. M. T. Migawa and E. E. Swayze, Org. Lett., 2, 3309 (2000).

    Article  CAS  Google Scholar 

  26. G. P. Sagitullina, L. V. Glyzdinskaya, G. V. Sitnikova, and R. S. Sagitullin, Khim. Geterotsikl. Soed., 1518 (2002). [Chem. Heterocycl. Comp., 38, 1336 (2002)].

    Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to G. P. Sagitullina.

Additional information

* For Communication 8, see [1].

** Deceased.

Translated from Khimya Geterotsiklicheskikh Soedinenii, No. 10, 1551-1558, October, 2010.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sagitullina, G.P., Garkushenko, A.K., Glyzdinskaya, L.V. et al. NitropyridineS. 9*. Synthesis of substituted 3-amino-5-nitropyridines. Chem Heterocycl Comp 46, 1255–1261 (2011).

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: