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Pictet-spengler reaction in the synthesis of condensed benzodiazepines. 2.* Synthesis of new derivatives of 11,12-dihydroquinazoline-[3,2-c][2, 3]benzodiazepin-14(6H)-ones

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Chemistry of Heterocyclic Compounds Aims and scope

New derivatives of dihydroquinazoline[3,2-c][2, 3]benzodiazepin-14(6H)-ones were synthesized using the Pictet-Spengler reaction of 3-amino-2-(3,4-dimethoxybenzyl)quinazolin-4(3H)-one with aliphatic and heterocyclic aldehydes in acid media.

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Correspondence to A. S. Tolkunov.

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*For Communication 1, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 882-893, June, 2010.

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Tolkunov, A.S., Bogza, S.L. Pictet-spengler reaction in the synthesis of condensed benzodiazepines. 2.* Synthesis of new derivatives of 11,12-dihydroquinazoline-[3,2-c][2, 3]benzodiazepin-14(6H)-ones. Chem Heterocycl Comp 46, 711–720 (2010). https://doi.org/10.1007/s10593-010-0573-3

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  • DOI: https://doi.org/10.1007/s10593-010-0573-3

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