Chemistry of Heterocyclic Compounds

, Volume 45, Issue 5, pp 623–626 | Cite as

Anniversaries and dates

Anniversaries and Dates


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Principal publications of G. Duburs in the field of heterocyclic chemistry (2004–2009)

  1. 1.
    J. Briede, M. Stiviriņa, D. Stoldere. E. Bisenieks, J. Ulkdriķis, J. Poikāns, N, Makarova, and G. Duburs, Effect of new and known 1,4-dihydropyridine derivatives on blood glucose levels in normal and streptozoticin-induced diabetic rate, Cell. Biochem. Funct., 22, 219–224 (2004).CrossRefGoogle Scholar
  2. 2.
    M. A. S. Fernandes, M. S. Santos, J. M. Moreno, G. Duburs, C. R. Oliviera, and A. F. Vicente. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes in ion permeability, J. Biochem. Mol. Toxicol., 18, 162–169 (2004).CrossRefGoogle Scholar
  3. 3.
    B. Jansone, R. Muceniece, V. Kluša, Š. Svirskis, R. Petrovska, G. Duburs, and J. E. S. Wikberg, The non-peptide compound cerebrocrast is a highly effective melanocortin MC4 receptor agonist and inhibits feeding, Proc. Latv. Acad. Sci., Sect. B, 58, 103–108 (2004).Google Scholar
  4. 4.
    A. Sobolev, M. C. R. Franssen, G. Duburs, and Ae. De Groot, Chemoenzymatic synthesis of enantiopure 1,4-dihydropurine derivatives, Biocatal. Biotransform., 22, 231–252 (2004).CrossRefGoogle Scholar
  5. 5.
    E. V. Ivanov, T. V. Ponomareva, G. N. Merkushev, I. K. Romanovich, G. Ya. Dubur, E. A. Bisenieks, Ya. R. Uddrikis, and Ya. Ya. Poikans, Radiomodification properties of derivatives of 1,4-dihydropyridine and 1,2,3,4,5,6,7,8,9,10-decahydroacridin-1,8-dione, Radiatsionnaya Biologiya. Radioekologiya, 44, 550–559 (2004).Google Scholar
  6. 6.
    B. Turovska, J. Stradins, I. Turovskis, A, Plotniece, A. Shmidlers, and G. Duburs, Electrochemical oxidation of analogs of gene transfection agents – the compounds containing 1,4-dihydropyridine and pyridinium cycles, Khim. Geterotsikl. Soedin., 880–886 (2004); Chem. Heterocycl. Comp., 40, 753–758 (2004).Google Scholar
  7. 7.
    Z. Kalme, R. Zhalubovskis, A. Shmidlers, J. Celmins, and G. Duburs, Synthesis of 6-bromomethyl-substituted derivatives of pyridine-2(1H)-ones and their reactions with nucleophiles, Khim. Geterotsikl. Soedin., 1006–1013 (2004). [Chem. Heterocycl. Comp., 40, 862–868 (2004)].Google Scholar
  8. 8.
    E. Bisenieks. J. Udrikis, and G. Duburs, Reaction of 3,5-dicarbonyl-substituted 1,4-dihydrpyridines with hydrazine hydrate, Khim. Geterotsikl. Soedin., 1014–1021 (2004). [Chem. Heterocycl. Comp., 40, 869–875 (2004)].Google Scholar
  9. 9.
    A. Krauze, L. Baumane, L. Sīle, L. Černova, M. Viļums, R. Vītoliņa, G. Duburs, and J. Stradins, Synthesis, cardiovascular activity, and electrochemical oxidation of of 5-ethoxycarbonyl-2-methylthio-1,4-dihydro-3-carbonitriles, Khim. Geterotsikl. Soedin., 1022–1035 (2004). [Chem. Heterocycl. Comp., 40, 876–887 (2004)].Google Scholar
  10. 10.
    A. Sobolev, R. Zhalubovskis, M. C. R. Franssen, B. Vigante, B. Chekavichus, G. Duburs, and Ae. de Groot, Candida rugosa lipase-catalysed kinetic resolution of 3-(isobutyryloxy)methyl-4-[2-(difluoro-methoxy)phenyl]-2-methyl-5,5-dioxo-1,4-dihydrobenzothieno[3,2-b]pyridine-3-carboxylate, Khim. Geterotsikl. Soedin., 1081–1088 (2004). [Chem. Heterocycl. Comp., 40, 931–937 (2004)].Google Scholar
  11. 11.
    E. Bisenieks, J. Uldriķis, and G. Duburs, 3,5-Dicyano-1,4-dihydropyridines as a source for the preparation of pyrazole and pyrazole[3,4-b]pyridine derivatives, Heterocycl. Commun., 11, 9–12 (2005).Google Scholar
  12. 12.
    M. A. S. Fernandes, A. S. Jurado, R. A. Videira, M. S. Santos, A. J. M. Moreno, A. Velena. G. Duburs, C. R. Oliveira, and J. A. F. Vicentem, Cerebrocast promotes the co-transport of H+ and Cl- in rat liver mitochondria. Mitochondrion, 5, 341–351 (2005).CrossRefGoogle Scholar
  13. 13.
    L. Klimavičiusa, V. Kluša, G. Duburs, A. Kaasic, A. Kalda, and A. Zharkovsky, Neuroprotective (oxygen-glucose deprivation model) and neurotrophic effects of novel 1,4-dihydropyridine derivatives in cerebellar granule cells, Proc. Latv. Acad. Sci., Sect. B, 59, 169–174 (2005).Google Scholar
  14. 14.
    A. Krauze, I. Šturms, J. Popelis, L. Sīle, V. Kluša, and G. Duburs, Synthesis and properties of methyl 4,6-diaryl-2(3H)-thioxo-1,4-dihydropyridine-3-carboxylates, Heterocycl. Commun., 11, 37–42 (2005).Google Scholar
  15. 15.
    A. Krauze, R. Vitolina, V. Garaliene, L. Sīle, V. Kluša, and G. Duburs, 5-(1-Pyridinio)-4,5-trans-1,4,5,6-tetrahydropyridine-2-thiolates. Eur. J. Med. Chem., 40, 1163–1167 (2005).CrossRefGoogle Scholar
  16. 16.
    N. I. Ryabokon, R. I. Goncharova, G. Duburs, and J. Rzeszowska-Wolny, A 1,3-dihydropyridine reduces DNA damage and stimulates DNA repair in human cells in vitro. Mutation Research, 587, 52–58 (2005).Google Scholar
  17. 17.
    L. Baumane, A. Krauze, S. Belyakov, L. Sile, L. Chernova, M. Grīga, G. Duburs, and J. Stradins, Synthesis, structure, and electrochemical characteristics of nitriles of 4-aryl-2-carbamoylmethylthio-5-ethoxycarbonyl-1,4-dihydropyridine-3-carboxylic acids, Khim. Geterotsikl. Soedin., 416–428 (2005). [Chem. Heterocycl. Comp., 41, 362–372 (2005)].Google Scholar
  18. 18.
    A. Krauze, L. Sīle, R. Danne, and G. Duburs, Synthesis and properties of 7-acetyl-8-aryl-9-cyano-3-hydroxy-6-methyl-3,4-dihydro-2H,8H-pyrido[2,1-b][1,3]thiazines, Khim. Geterotsikl. Soedin., 1394–1399 (2005). [Chem. Heterocycl. Comp., 41, 1189–1194 (2005)].Google Scholar
  19. 19.
    V. Klusa, L. Klimaviciusa, G. Duburs, J. Poikans, and A. Zharkovsky, Anti-neurotoxic effects of tauropyrone, a taurine analogue, in: S. S Oja and P. Saransaari (editors), Taurine 6. Advances in experimental medicine and biology, Vol. 583, Springer, New York, 2006, pp. 499–508.Google Scholar
  20. 20.
    A. Krauze, L. Chernova, M. Viļums, L. Sīle, and G. Duburs, Green one-pot multicomponent synthesis of methyl 4-aryl-6-carbamoylmethylthio-5-cyano-2-methyl-1,4-dihydropyridine-3-carboxylates, Heterocycl. Commun., 12, 281–286 (2006).Google Scholar
  21. 21.
    A. Vaitkuviene, A. Ulinskaite, R. Meškys, G. Duburs, V. Kluša, and E. Liutkevičius, Study of the interaction of 1,4-dihydropyridine derivatives with glucocorticoid hormone receptors from the rat liver. Pharmacol. Rep., 58, 551–558 (2006).Google Scholar
  22. 22.
    J. A. F. Vicente, G. Duburs, V. Z. Kluša, J. Briede, L. Klimavičiusa, A. Zharkovsky, and M. A. S. Fernandes, Cerebrocast as a neuroprotective, anti-diabetic, and mitochondrial bioenergetic effector. A putative mechanism of action, in: A. J. M. Moreno (editor), Mitochondrial Pharmacology and Toxicology, Transworld Research Network, Kerala, 2006, p.185–197.Google Scholar
  23. 23.
    J. Briede and G. Duburs, Protective effect of cerebrocrast on rat brain ischaemia induced by occlusion of both carotid arteries, Cell Biochem. Funct., 25, 203–210 (2007).CrossRefGoogle Scholar
  24. 24.
    J. Briede, M. Stivrina, Dz. Stoldere, B. Vigante, and G. Duburs, Effect of cerebrocrast, a new long-acting compound on blood glucose and insulin levels in rate when administered before and after STZ-induced diabetes mellitus, Cell Biochem. Funct., 25, 673–680 (2007).CrossRefGoogle Scholar
  25. 25.
    I. Klimaviciusa, A. Kalda, A. Kaasic, A. Zharkovsky, E. Bisenieks, J. Uldrikis, G. Duburs, and V. Klusa. Neuroprotective activity of 1,4-dihydropyridines: structural determinant, Proc. Latvian Acad. Sci., Sect. B., 61, 33–37 (2007).Google Scholar
  26. 26.
    A Krauze, R. Danne, M. Viļums, Z. Kalme, L. Černova, L. Sīle, and G. Duburs, Synthesis of new partially hydrogenated 6-alkylthio-2,4-diaryl-3-ethoxycarbonylpyridine-5-carbonitriles, Latv. J. Chem., 183–188 (2007).Google Scholar
  27. 27.
    L. Klimaviciusa, V. Klusa, G. Duburs, A. Kaasic, A. Kalda, and A. Zharkovsky, Distinct effects of atypical 1,4-dihydropyridines on 1-methyl-4-phenylpyridinium induced toxicity, Cell. Biochem. Funct., 25, 15–21 (2007).CrossRefGoogle Scholar
  28. 28.
    H. Kažoka, A. Krauze. M. Viļums, L. Černova, L. Sīle, and G. Duburs, Synthesis and investigation of the stability of esters of 6′-carbamoylmethylthio-5′-cyano-1′,4′-dihydro-3,4′- and -4,4′-bipyridin-3′-carboxylic acids, I. 6′-Carbamomylmethylthio-5′-cyano-1′,4′-dihydro-3,4′-bipyridine-3′-carboxylate esters, Khim. Geterotsikl. Soedin., 59–68 (2007). [Chem. Heterocycl. Comp., 43, 50–57 (2007)].Google Scholar
  29. 29.
    B. Vigante, G. Tirzitis, D. Tirzite, B. Chekavichus, Ya. Uldrikis, A. Sobolev, and G, Duburs, 4-(10-Methyl-10H-phenothazin-3-yl)1,4-dihydropyridines, 4,5-dihydroindeno[1,2-b]- and 5,5-dioxo-4,5-dihydrobenzothieno-[3,2-b]pyridines, Khim. Geterotsikl. Soedin., 280–288 (2007). [Chem. Heterocycl. Comp., 43, 225–232 (2007)].Google Scholar
  30. 30.
    A. Krauze, M. Viļums, L. Sīle, and G. Duburs, Alternative products in one-pot reaction of benzylidenemalononitrile, N-methyl-2-thiocarbamoylacetamide, and ω-bromoacetophenone, Khim. Geterotsikl. Soedin., 777–781(2007). [Chem. Heterocycl. Comp., 43, 635–657(2007).Google Scholar
  31. 31.
    Z. Kalme, A. Šmidlers, J. Celmiņš, E. Liepinsh, A. Krauze, and G. Duburs, Unexpected bromination reaction of of 3,4-dihydropyridin-2(H)-ones with N-bromosuccinimide, Khim. Geterotsikl. Soedin., 786–788 (2007). [Chem. Heterocycl. Comp., 43, 662–664 (2007)].Google Scholar
  32. 32.
    H. Kažoka, A. Krauze, M. Viļums, L. Černova, L. Sīle, and G. Duburs, Synthesis and investigation of the stability of esters of 6′-carbamoylmethylthio-5′-cyano-1′,4′-dihydro-3,4′- and -4,4′-bipyridin-3′-carboxylic acids. 2. 6′-Carbamomylmethylthio-5′-cyano-1′,4′dihydro-4,4′-bipyridine-3′-carboxylates, Khim. Geterotsikl. Soedin., 841–848 (2007). [Chem. Heterocycl. Comp., 43, 708–714 (2007)].Google Scholar
  33. 33.
    J. Briede, M. Stivrina, B. Vigante, Dz. Stoldere, and G. Duburs, Acute effect of antidiabetic 1,4-dihydropyridine compound cerebrocrast on cardiac function and glucose metabolism in the isolated, perfused normal rat heart, Cell. Biochem. Funct., 26, 238–245 (2008).CrossRefGoogle Scholar
  34. 34.
    J. Briede, M. Stivrina, B. Vigante, Dz. Stoldere, and G. Duburs, Effect of cerebrocrast on body and organ weights, food and water intake, and urine output o normal rats, Cell. Biochem. Funct., 26, 908–915 (2008).CrossRefGoogle Scholar
  35. 35.
    B. Cekavicus, B. Vigante, E. Liepinsh, R. Vilskersts, A. Sobolev, S. Belyakov, A. Plotniece, K. Mekss, and G. Duburs, Benzo[b]thiophen-3(2H)-one 1,1-dioxide – a versatile reagent in the synthesis of spiroheterocycles, Tetrahedron, 64, 9947–9952 (2008).CrossRefGoogle Scholar
  36. 36.
    G. Duburs, B. Vīgante, A. Plotniece, A. Krauze, A. Sobolev, J. Briede, V. Kluša, and A. Velēna, Dihydropyridine derivatives as bioprotectors, Chemistry Today/Chimica Oggi, 26, 68–70 (2008).Google Scholar
  37. 37.
    M. A. S. Fernandes, S. P. S. Pereira, A. S. Jurado, J. B. Custódio, M. S. Santos, A. J. M. Moreno, G. Duburs, and J. A. F. Vicente, Comparitive effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: Relevance to the length of the alkoxy chain in positions 3 and 5 of the DHP ring, Chem.-Biol. Interactions, 173, 195–204 (2008).CrossRefGoogle Scholar
  38. 38.
    J. Pupure, S. Isajevs, V. Gordjushina, I. Taivans, J. Rumaks, S. Svirskis, A. Kratovska, Z. Dzirkale, J. Pilipenko, G. Duburs, and V. Klusa, Distinct influence of atypical 1,4-dihydropyridine compounds in azidothymidine-induced neuro- and cardiotoxicity in mice ex vivo. Basic Clin. Pharmacol. Toxicol., 103, 401–406 (2008).CrossRefGoogle Scholar
  39. 39.
    N. I. Ryabokon, R. I. Goncharova, G. Duburs, R. Hancock, and J. Rzeszowska-Wolny, Changes in poly-(ADP-ribose) level modulate the kinetics of DNA strand break rejoining, Mutat. Res., 637, 173–181 (2008).Google Scholar
  40. 40.
    I. Kalviņš, L. Sīle, A. Krauze, A. Černobrovijs, Z. Andžāns, G. Duburs, Viena reactors metode ftalimidoamlodipīna iegūšanai jonu šķidrumu promotētās reakcijās (Ionic liquid promoted one pot method of preparation of phthalimidoamlodipine), LV P-08-80 (2008).Google Scholar
  41. 41.
    I. Kalviņš, L. Sīle, A. Krauze, A. Černobrovijs, and G. Duburs, Jauna metode ftalimidoamlodipīna iegūšanai jonu šķidrumu promotētās reakcijās, (A new ionic liquid promoted method of preparation of phthalimidoamlodipine). LV P-08-81 (2008).Google Scholar
  42. 42.
    I. Kalviņš, L. Sīle, A. Krauze, A. Černobrovijs, Z. Kalme and G. Duburs, Trīs komponentu metode ftalimidoamlodipīna iegūšanai jonu šķidrumu promotētās reakcijās, (Ionic liquid promoted three component method of preparation of phthalimidoamlodipine), LV P-08-82 (2008).Google Scholar
  43. 43.
    A. Krauze, E. Liepinsh, M. Viļums, and G. Duburs, A new regioselective synthesis of 2-methoxy-methyl-3-oxo-2,3-dihydro-7H-thiazolo[3,2-a]pyridine-8-carboxylic acid methylamide, Khim. Geterotsikl. Soedin., 309–311 (2009). [Chem. Heterocycl. Comp., 45, 250–252 (2009)].Google Scholar

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© Springer Science+Business Media, Inc. 2009

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