1,3-Dipolar cycloaddition of nitrile oxides generated in situ in the presence of variously substituted N-arylmaleimides and N-benzylmaleimide provides new pyrrolo[3,4-d]izoxazoline-4,6-diones in good yields. The whole procedure could be performed in a practical and efficient one-pot operation. All the cycloadducts were isolated in excellent yields and identified by spectral studies.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 444–448, March, 2009.
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Rajput, J., Singh, B. & Singal, K.K. one-pot synthesis of pyrrolo-[3,4-d]isoxazoline-4,6-diones via nitrile oxides. Chem Heterocycl Comp 45, 361–364 (2009). https://doi.org/10.1007/s10593-009-0265-z
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DOI: https://doi.org/10.1007/s10593-009-0265-z