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Synthesis of 2-spiro-(1,2-dihydroperimid-2-yl)-5,5-dialkyl-2,3,5,6-tetrahydropyrrolo[2,1-a]-isoquinolin-3-ones

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Chemistry of Heterocyclic Compounds Aims and scope

2,3-Dioxpyrrolo[2,1-a]isoquinolines react with 1,8-naphthalenediamine in 2-propanol in the presence of p-toluenesulfonic acid to give 2-spiro-(1,2-dihydroperimid-2-yl)-5,5-dialkyl-2,3,5,6-tetrahydro-pyrrolo[2,1-a]isoquinolin-3-ones whose structure was confirmed by X-ray analysis.

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Correspondence to O. V. Surikova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1849–1854, December, 2008.

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Surikova, O.V., Aliev, Z.G. & Mikhailovskii, A.G. Synthesis of 2-spiro-(1,2-dihydroperimid-2-yl)-5,5-dialkyl-2,3,5,6-tetrahydropyrrolo[2,1-a]-isoquinolin-3-ones. Chem Heterocycl Comp 44, 1500–1504 (2008). https://doi.org/10.1007/s10593-009-0207-9

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  • DOI: https://doi.org/10.1007/s10593-009-0207-9

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