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Cyclocondensation of N-aryl-3-oxobutanethioamides with 5-amino-3-R-4-R1-pyrazoles

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Chemistry of Heterocyclic Compounds Aims and scope

The cyclocondensation products of N-aryl-3-oxobutanethioamides with 5-amino-3-R-4-R1-pyrazoles are 4-(arylamino)-2-methyl-7-R-8-R1-pyrazolo[1,5-a]pyrimidine and pyrazolo[1,5-a]pyrimidine-4-thione derivatives, the ratio of which depends on the nucleophilicity of the starting 5-amino-3-R-4-R1-pyrazoles and the presence of a proton donor solvent.

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Authors and Affiliations

  1. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev, 02660, Ukraine

    V. N. Britsun

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  1. V. N. Britsun
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Correspondence to V. N. Britsun.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1550-1555, October, 2008.

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Britsun, V.N. Cyclocondensation of N-aryl-3-oxobutanethioamides with 5-amino-3-R-4-R1-pyrazoles. Chem Heterocycl Comp 44, 1262–1266 (2008). https://doi.org/10.1007/s10593-009-0168-z

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  • DOI: https://doi.org/10.1007/s10593-009-0168-z

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