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Synthesis of unnatural amino acids containing the 3,7-diazabicyclo-[3,3,1]nonane unit

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Unnatural amino acids containing the 3,7-diazabicyclo[3,3,1]nonane unit were synthesized in one step by the reaction of diethyl 3-oxoglutarate, bis(methoxycarbonylmethyl) sulfone, with formaldehyde and primary amino acids under conditions of the Mannich reaction.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Science Center, Russian Academy of Sciences, Ufa, 450054, Russia

    D. R. Latypova, L. I. Vlasova, N. Z. Baibulatova, A. N. Lobov, L. V. Spirikhin & V. A. Dokichev

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  1. D. R. Latypova
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  2. L. I. Vlasova
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  3. N. Z. Baibulatova
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  4. A. N. Lobov
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  5. L. V. Spirikhin
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  6. V. A. Dokichev
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Corresponding author

Correspondence to V. A. Dokichev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, 1236–1244, August, 2008.

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Latypova, D.R., Vlasova, L.I., Baibulatova, N.Z. et al. Synthesis of unnatural amino acids containing the 3,7-diazabicyclo-[3,3,1]nonane unit. Chem Heterocycl Comp 44, 996–1002 (2008). https://doi.org/10.1007/s10593-008-0146-x

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  • DOI: https://doi.org/10.1007/s10593-008-0146-x

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