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Direction of isomerization of 5-hydroxy-3-propargylthio-1,2,4-triazines according to 1H/15N heteronuclear multiple bond correlation (HMBC) spectra

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Abstract

We have studied isomerization of 6-substituted 5-hydroxy-3-propargylthio-1,2,4-triazines using base catalysis. We have used NMR correlation spectroscopy (1H/15N HMBC spectra) to prove the structure of the regioisomer formed. The type of regioisomer formed (3,6-dimethylthiazolo[3,2-b]-1,2,4-triazin-7-one) allows us to say that isomerization occurs as a direct propynyl rearrangement.

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Authors and Affiliations

  1. Scientific-Research Institute of Chemistry, St. Petersburg State University, Petrodvorets, St. Petersburg, 198504, Russia

    V. Yu. Smutin, V. A. Gindin & N. O. Sablina

Authors
  1. V. Yu. Smutin
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  2. V. A. Gindin
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  3. N. O. Sablina
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 453–457, March, 2006.

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Smutin, V.Y., Gindin, V.A. & Sablina, N.O. Direction of isomerization of 5-hydroxy-3-propargylthio-1,2,4-triazines according to 1H/15N heteronuclear multiple bond correlation (HMBC) spectra. Chem Heterocycl Compd 42, 403–407 (2006). https://doi.org/10.1007/s10593-006-0100-8

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  • DOI: https://doi.org/10.1007/s10593-006-0100-8

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