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4-Hydroxy-2-quinolones. 90. Synthesis and antitubercular activity of 4-methyl-2-thiazolylamides of halo-substituted 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acids

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Several variants were studied for the synthesis of esters of halogen derivatives of 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acids, whose reaction with 2-amino-4-methylthiazole gives the corresponding hetarylamides. Results are given for a study of the antitubercular activity of these products.

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Authors and Affiliations

  1. National Pharmaceutical University, 61002, Kharkov, Ukraine

    I. V. Ukrainets, L. V. Sidorenko, L. A. Petrushova & O. V. Gorokhova

Authors
  1. I. V. Ukrainets
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  2. L. V. Sidorenko
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  3. L. A. Petrushova
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  4. O. V. Gorokhova
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Additional information

Communication 89, see ref. [1].

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 71–76, January, 2006.

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Ukrainets, I.V., Sidorenko, L.V., Petrushova, L.A. et al. 4-Hydroxy-2-quinolones. 90. Synthesis and antitubercular activity of 4-methyl-2-thiazolylamides of halo-substituted 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acids. Chem Heterocycl Compd 42, 64–69 (2006). https://doi.org/10.1007/s10593-006-0048-8

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  • DOI: https://doi.org/10.1007/s10593-006-0048-8

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