Abstract
4-Chloro-2-oxo-1,2-dihydroquinoline-3-carboxylic acids and their esters react with aminopyridines in refluxing DMF to give the corresponding 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid pyridylamides. Their structures were proved by 1H NMR and mass spectroscopy, counter synthesis, and by X-ray analysis. A possible mechanism is proposed for the indicated chemical reaction.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1362–1371, September, 2005.
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Ukrainets, I.V., Sidorenko, L.V., Slobodzyan, S.V. et al. 4-Hydroxyquinol-2-ones. 87. Unusual Synthesis of 1-R-4-Hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic Acid Pyridylamides. Chem Heterocycl Compd 41, 1158–1166 (2005). https://doi.org/10.1007/s10593-005-0296-z
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DOI: https://doi.org/10.1007/s10593-005-0296-z