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New Synthesis of 3-(2-Furyl)phthalides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3-(2-Furyl)phthalides were synthesized for the first time by the reaction of 2-formylbenzoic acids with furan derivatives in the presence of an acidic catalyst. It was found that the reaction of 2-formylbenzoic acids and 2-alkylfurans in aqueous dioxane in the presence of perchloric acid leads to a mixture of 2-carboxyaryldifurylmethanes and 3-furylphthalides, which can be separated easily by preparative column chromatography.

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Authors and Affiliations

  1. Scientific-Research Institute of Chemistry of Heterocyclic Compounds, Kuban State Technological University, Krasnodar, 350072, Russia

    A. S. Dmitriev, A. S. Pilipenko, V. T. Abaev & A. V. Butin

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  1. A. S. Dmitriev
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  2. A. S. Pilipenko
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  3. V. T. Abaev
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  4. A. V. Butin
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1302–1304, September, 2005.

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Dmitriev, A.S., Pilipenko, A.S., Abaev, V.T. et al. New Synthesis of 3-(2-Furyl)phthalides. Chem Heterocycl Compd 41, 1102–1104 (2005). https://doi.org/10.1007/s10593-005-0286-1

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  • DOI: https://doi.org/10.1007/s10593-005-0286-1

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