Abstract
A three component “one-pot” condensation of 1,2-ethylenedioxybenzene and RCN nitriles with isobutylene oxide, isobutyraldehyde, or cyclohexanecarboxaldehyde in the presence of conc. H2SO4 gives 1-R-3,3-dialkyl-6,7-ethylenedioxy-3,4-dihydroisoquinolines.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1198–1203, August, 2005.
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Glushkov, V.A., Rozhkova, Y.S., Vakhrin, M.I. et al. 1-R-3,3-dialkyl-6,7-ethylenedioxy-3,4-dihydroisoquinolines. Chem Heterocycl Compd 41, 1022–1026 (2005). https://doi.org/10.1007/s10593-005-0272-7
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DOI: https://doi.org/10.1007/s10593-005-0272-7