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Synthesis and Some Transformations of 2-(3-Amino-1-Phenylpropyl)furan

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A preparative method was developed for the synthesis of ethyl furfurylidenecyanoacetate. Its condensation with phenylmagnesium bromide gave ethyl α-cyano-β-(2-furyl)hydrocinnamate, the decarboxylation of which led to β-(2-furyl)hydrocinnamonitrile. Reduction of this nitrile with lithium aluminum hydride gave 2-(3-amino-1-phenylpropyl)furan. Some of its transformations were studied.

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REFERENCES

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Authors and Affiliations

  1. A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan, Armenia

    N. S. Arutyunyan, L. A. Akopyan, G. A. Gevorgyan & G. M. Snkhchyan

  2. Molecular Structure Research Center, National Academy of Sciences of the Republic of Armenia, Erevan, 375014, Armenia

    G. A. Panosyan

Authors
  1. N. S. Arutyunyan
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  2. L. A. Akopyan
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  3. G. A. Gevorgyan
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  4. G. M. Snkhchyan
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  5. G. A. Panosyan
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 517–521, April, 2005.

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Arutyunyan, N.S., Akopyan, L.A., Gevorgyan, G.A. et al. Synthesis and Some Transformations of 2-(3-Amino-1-Phenylpropyl)furan. Chem Heterocycl Compd 41, 437–441 (2005). https://doi.org/10.1007/s10593-005-0166-8

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  • DOI: https://doi.org/10.1007/s10593-005-0166-8

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