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Gene Flow and Adaptive Potential in Drosophila melanogaster

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Abstract

Gene flow among historically isolated populations is expected to increase genetic diversity and consequently the ability of populations to adapt to environmental changes. Few experimental studies, however, have examined the relationship between gene flow and the adaptive potential of populations. The increase in adaptive potential that occurs as a result of gene flow is expected to depend on the genetic variance among populations that undergo genetic exchange. In the present study, we compared observed and expected changes in adaptive potential (as measured by the selection response of sternopleural bristle number) that occur as a result of gene flow among experimental populations of Drosophila melanogaster. We examined the effect of limited immigration (m = 0.05 over 3 generations) among a set of experimentally isolated lineages, in addition to the effect of complete hybridization among lineages. As expected, we found that limited immigration and hybridization both yielded increases in adaptive potential. However, whereas the effect of limited immigration agreed well with theoretical expectations, the increase in adaptive potential following complete hybridization of lineages was significantly less than expected. We discuss these findings in relation to endangered species conservation efforts, particularly with respect to the goal of maximizing the retention of adaptive potential within managed populations.

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References

  • FW Allendorf (1986) ArticleTitleGenetic drift and the loss of alleles versus heterozygosity. Zoo Biol. 5 181–190 Occurrence Handle10.1002/zoo.1430050212

    Article  Google Scholar 

  • KD Atkins R Thompson (1986) ArticleTitlePredicted and realized responses to selection for an index of bone length and body weight in scottish blackface sheep. I. Responses in the index and component traits Anim. Prod. 43 421–435

    Google Scholar 

  • SJ Ball M Adams HP Possingham MA Keller (2000) ArticleTitleThe genetic contribution of single male immigrants to small, inbred populations: A laboratory study using Drosophila melanogaster Heredity 84 677–684 Occurrence Handle10.1046/j.1365-2540.2000.00721.x Occurrence Handle1:CAS:528:DC%2BD3cXmsVSisLk%3D Occurrence Handle10886383

    Article  CAS  PubMed  Google Scholar 

  • WJ Boecklen (1986) ArticleTitleOptimal design of nature reserves: consequences of genetic drift. Biol. Conserv. 38 323–338 Occurrence Handle10.1016/0006-3207(86)90058-3

    Article  Google Scholar 

  • EH Bryant VL Backus ME Clark DH Reed (1999) ArticleTitleExperimental tests of captive breeding for endangered species Conserv. Biol. 13 1487–1496

    Google Scholar 

  • R Burger M Lynch (1995) ArticleTitleEvolution and extinction in a changing environment – a quantitative-genetic analysis Evolution 49 151–163

    Google Scholar 

  • P Buri (1956) ArticleTitleGene frequency in small populations of mutant Drosophila Evolution 10 367–402

    Google Scholar 

  • MG Bulmer (1985) The Mathematical Theory of Quantitative Genetics Clarendon Press Oxford

    Google Scholar 

  • JM Cheverud TT Vaughn LS Pletscher K King-Ellison J Bailiff E Adams C Erickson A Bonislawski (1999) ArticleTitleEpistasis and the evolution of additive genetic variance in populations that pass through a bottleneck Evolution 53 1009–1018

    Google Scholar 

  • JF Crow NE Morton (1955) ArticleTitleMeasurement of gene frequency drift in small populations Evolution 9 202–214

    Google Scholar 

  • D Ebert C Haag M Kirkpatrick M Riek JW Hottinger VI Pajunen (2002) ArticleTitleA selective advantage to immigrant genes in a Daphnia metapopulation Science 295 IssueID5554 485–488 Occurrence Handle10.1126/science.1067485 Occurrence Handle1:CAS:528:DC%2BD38XnvFWgtQ%3D%3D Occurrence Handle11799241

    Article  CAS  PubMed  Google Scholar 

  • NG Ehiobu ME Goddard JF Taylor (1989) ArticleTitleEffect of rate of inbreeding on inbreeding depression in Drosophila melanogaster Theor. Appl. Genet. 77 123–127

    Google Scholar 

  • DS Falconer TFC Mackay (1996) Introduction to Quantitative Genetics EditionNumber4 Longman Harlow, UK

    Google Scholar 

  • J Felsenstein (1971) ArticleTitleInbreeding and variance effective numbers in populations with overlapping generations Genetics 68 581–597 Occurrence Handle1:STN:280:CS2D2cvnsVE%3D Occurrence Handle5166069

    CAS  PubMed  Google Scholar 

  • RA Fisher (1930) The Genetical Theory of Natural Selection Clarendon Press Oxford

    Google Scholar 

  • O Flagstad CW Walker C Vila AK Sundqvist B Fernholm AK Hufthammer O Wiig I Koyola H Ellegren (2003) ArticleTitleTwo centuries of the scandinavian wolf population: Patterns of genetic variability and migration during an era of dramatic decline Mol. Ecol. 12 IssueID4 869–880 Occurrence Handle10.1046/j.1365-294X.2003.01784.x Occurrence Handle1:CAS:528:DC%2BD3sXjtl2mtro%3D Occurrence Handle12753208

    Article  CAS  PubMed  Google Scholar 

  • R Frankham JD Ballou DA Briscoe (2002) Introduction to Conservation Genetics Cambridge University Press Cambridge

    Google Scholar 

  • IR Franklin (1980) Evolutionary change in small populations ME Soulé BA Wilcox (Eds) Conservation Biology: An Evolutionary-Ecological Perspective Sinauer Sunderland, MA 135–150

    Google Scholar 

  • IR Franklin R Frankham (1998) ArticleTitleHow large must populations be to retain evolutionary potential Anim. Conserv. 1 69–71 Occurrence Handle10.1017/S1367943098211103

    Article  Google Scholar 

  • PA Fuerst T Maruyama (1986) ArticleTitleConsiderations on the conservation of alleles and of genic heterozygosity in small managed populations Zoo Biol. 5 171–179 Occurrence Handle10.1002/zoo.1430050211

    Article  Google Scholar 

  • CJ Goodnight (1988) ArticleTitleEpistasis and the effect of founder events on the additive genetic variance. Evolution 42 441–454

    Google Scholar 

  • Hoffman AA, Parsons PA (1991) Evolutionary Genetics and Environmental Stress. Oxford University Press.

  • PK Ingvarsson (2001) ArticleTitleRestoration of genetic variation lost – the genetic rescue hypothesis. Trends Ecol. Evol. 16 62–63 Occurrence Handle10.1016/S0169-5347(00)02065-6 Occurrence Handle11165697

    Article  PubMed  Google Scholar 

  • PK Ingvarsson MC Whitlock (2000) ArticleTitleHeterosis increases the effective migration rate Proc. R. Soc. Lond. B 267 1321–1326 Occurrence Handle10.1098/rspb.2000.1145 Occurrence Handle1:STN:280:DC%2BD3M%2FntV2lsQ%3D%3D

    Article  CAS  Google Scholar 

  • CS Jones LR Noble JS Jones H Tegelstrom GS Triggs RJ Berry (1995) ArticleTitleDifferential male genetic success determines gene flow in an experimentally manipulated mouse population Proc. R. Soc. Lond. B 260 251–256 Occurrence Handle1:STN:280:ByqA2Mjjs1A%3D

    CAS  Google Scholar 

  • Kauffman B, Wool D (1992) Gene flow by immigrants into isolated recipient populations: A laboratory model using flour beetles. Genetica 85, 1992.

  • M Kimura (1955) ArticleTitleRandom genetic drift in multi-allelic locus. Evolution 9 419–435

    Google Scholar 

  • SE Kerr S Wright (1954) ArticleTitleExperimental studies of the distribution of gene frequencies in very small populations of Drosophila melanogaster. I. Forked Evolution 8 172–177

    Google Scholar 

  • RC Lacy DB Lindenmayer (1995) ArticleTitleA simulation study of the impacts of population subdivision on the mountain brushtail possum Trichosurus caninus ogilby in south-eastern Australia. II. Loss of genetic variation within and between subpopulations Biol. Conserv. 73 131–142 Occurrence Handle10.1016/0006-3207(95)91940-Y

    Article  Google Scholar 

  • R Lande (1992) ArticleTitleNeutral theory of quantitative genetic variance in an island model with local extinction and colonization Evolution 46 381–389

    Google Scholar 

  • R Lande (1995) Breeding plans for small populations based on the dynamics of quantitative genetic variance JD Ballou M Gilpin TJ Foose (Eds) Population Management for Survival and Recovery: Analytical Methods and Strategies in Small Population Conservation Columbia University Press New York 318–340

    Google Scholar 

  • R Lande GF Barrowclough (1987) Effective population size, genetic variation, and their use in population management ME Soulé (Eds) Viable Populations for Conservation Cambridge University Press Cambridge, UK 87–123

    Google Scholar 

  • M Lynch (1988) ArticleTitleThe rate of polygenic mutation. Genet. Res. 51 137–148 Occurrence Handle1:STN:280:BieA3Mzms1Y%3D Occurrence Handle3410317

    CAS  PubMed  Google Scholar 

  • M Lynch (1991) ArticleTitleThe genetic interpretation of inbreeding depression and outbreeding depression. Evolution 45 622–629

    Google Scholar 

  • M Lynch WG Hill (1986) ArticleTitlePhenotypic evolution by neutral mutation Evolution 40 915–935

    Google Scholar 

  • T Maruyama (1970) ArticleTitleEffective number of alleles in a subdivided population. Theoret. Popul. Biol. 1 273–306 Occurrence Handle1:STN:280:CSyB2Mzntl0%3D

    CAS  Google Scholar 

  • DE McCauley MJ Wade (1981) ArticleTitleThe populational effects of inbreeding in Tribolium Heredity 46 59–67

    Google Scholar 

  • D Newman DA Tallmon (2001) ArticleTitleExperimental evidence for beneficial fitness effects of gene flow in recently isolated populations Conserv. Biol. 15 1054–1063 Occurrence Handle10.1046/j.1523-1739.2001.0150041054.x

    Article  Google Scholar 

  • C Parmesan TL Root MR Willig (2000) ArticleTitleImpacts of extreme weather and climate on terrestrial biota B. Am. Meteor. Soc. 81 443–450

    Google Scholar 

  • C Parmesan G Yohe (2003) ArticleTitleA globally coherent fingerprint of climate change impacts across natural systems Nature 421 37–42 Occurrence Handle10.1038/nature01286 Occurrence Handle1:CAS:528:DC%2BD3sXoslM%3D Occurrence Handle12511946

    Article  CAS  PubMed  Google Scholar 

  • L Partridge (1988) ArticleTitleThe rare male effect – what is its evolutionary significance Phil. Trans. R. Soc. Lond. 319 IssueID1196 525–539 Occurrence Handle1:STN:280:BiaD1Mbjt1c%3D

    CAS  Google Scholar 

  • C Ray (2001) ArticleTitleMaintaining genetic diversity despite local extinctions: Effects of population scale Biol. Conserv. 100 3–14 Occurrence Handle10.1016/S0006-3207(00)00202-0

    Article  Google Scholar 

  • A Robertson (1952) ArticleTitleThe effect of inbreeding on the variation due to recessive genes. Genetics 37 189–207

    Google Scholar 

  • RG Ruano LS Silvela C Lopez-Fanjul MA Toro (1996) ArticleTitleChanges in the additive variance of a fitness-related trait with inbreeding in Tribolium castaneum J. Anim. Breed. Genet. 113 93–97

    Google Scholar 

  • IJ Saccheri PM Brakefield (2002) ArticleTitleRapid spread of immigrant genomes into inbred populations Proc. R. Soc. Lond. B 269 IssueID1495 1073–1078 Occurrence Handle10.1098/rspb.2002.1963

    Article  Google Scholar 

  • ME Soulé (1987) Introduction ME Soulé (Eds) Viable Populations for Conservation Cambridge University Press Cambridge, UK 1–10

    Google Scholar 

  • D Spielman R Frankham (1992) ArticleTitleModeling problems in conservation genetics using captive Drosophila populations: Improvement of reproductive fitness due to immigration of one individual into small partially inbred populations Zoo Biol. 11 343–351 Occurrence Handle10.1002/zoo.1430110506

    Article  Google Scholar 

  • DA Tallmon G Luikart RS Waples (2004) ArticleTitleThe alluring simplicity and complex reality of genetic rescue Trends Ecol. Evol. 19 489–496 Occurrence Handle10.1016/j.tree.2004.07.003

    Article  Google Scholar 

  • CD Thomas A Cameron RE Green M Bakkenes LJ Beaumont YC Collingham BFN Erasmus MF Siqueira Particlede A Grainger L Hannah L Hughes B Huntley AS Jaarsveld Particlevan GF Midgley L Miles MA Ortega-Huerta AT Peterson OL Phillips SE Williams (2004) ArticleTitleExtinction risk from climate change Nature 427 IssueID6970 145–148 Occurrence Handle10.1038/nature02121 Occurrence Handle1:CAS:528:DC%2BD2cXhtFOgtQ%3D%3D Occurrence Handle14712274

    Article  CAS  PubMed  Google Scholar 

  • C Vila AK Sundqvist O Flagstad J Seddon S Bjornerfeldt I Kojola A Casulli H Sand P Wabakken H Ellegran (2002) ArticleTitleRescue of a severely bottlenecked wolf population by a single immigrant Proc. R. Soc. Lond. B 270 IssueID1510 91–97

    Google Scholar 

  • RS Waples (2002) Definition and estimation of effective population size in the conservation of endangered species SR Beissinger McCullough (Eds) Population Viability Analysis University of Chicago Press Chicago, IL 147–168

    Google Scholar 

  • RL Westemeier JD Brawn SA Simpson TL Esker RW Jansen JW Walk EL Kershner JL Bouzat KN Paige (1998) ArticleTitleTracking the long term decline and recovery of an isolated population Science 282 1695–1698 Occurrence Handle10.1126/science.282.5394.1695 Occurrence Handle1:CAS:528:DyaK1cXnslGgs7g%3D Occurrence Handle9831558

    Article  CAS  PubMed  Google Scholar 

  • MC Whitlock PC Phillips MJ Wade (1993) ArticleTitleGene interaction affects the additive genetic variance in subdivided populations with migration and extinction Evolution 47 1758–1769

    Google Scholar 

  • S Wright WE Kerr (1954) ArticleTitleExperimental studies of the distribution of gene frequencies in very small population’s of Drosophila melanogaster. II. Bar Evolution 8 225–240

    Google Scholar 

  • S Wright (1969) Evolution and the Genetics of Populations. II. The Theory of Gene Frequencies University of Chicago Press Chicago

    Google Scholar 

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  1. Department of Biological Sciences, Bowling Green State University, Life Science Building, Bowling Green, OH, 43403-0212, USA

    William R. Swindell & Juan L. Bouzat

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  1. William R. Swindell
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  2. Juan L. Bouzat
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Correspondence to Juan L. Bouzat.

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Swindell, W.R., Bouzat, J.L. Gene Flow and Adaptive Potential in Drosophila melanogaster. Conserv Genet 7, 79–89 (2006). https://doi.org/10.1007/s10592-005-8223-5

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  • DOI: https://doi.org/10.1007/s10592-005-8223-5

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