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Pulmonary lymphangitic sarcomatosis and a review of the literature

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Abstract

Intrapulmonary spread of a sarcoma via lymphatics is a rare cause of death in a young adult. A 31-year old man was admitted to our hospital complaining of dyspnea and malaise of 2 months’ duration. A chest radiography revealed bilateral hilar enlargement, and reticulonodular infiltrations. Thoracic CT-scans demonstrated mediastinal lymphadenopathy, thickening of interlobular septa, polygonal lines, and thickening of bronchovascular bundles. The diagnosis was made by open-lung biopsy. The patient died within 3 months after diagnosis. Pulmonary lymphangitic sarcomatosis is a rare but important manifestation of an angiosarcoma. Optimal treatment of these patients is not well defined, but a trial of chemotherapy may be warranted.

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Authors and Affiliations

  1. Department of Chest Diseases, Canakkale State Hospital, 17100, Canakkale, Turkey

    Tanseli Gonlugur

  2. Department of Thoracic Surgery, Sivas State Hospital, 58040, Sivas, Turkey

    Feride Sapmaz & Ozgur Katrancioglu

  3. Department of Chest Diseases, Onsekiz Mart Universitesi Tip Fakultesi, Onsekiz Mart University Medical School, Gogus Hastaliklari Anabilim Dali, 17100, Canakkale, Turkey

    Ugur Gonlugur

  4. Department of Pathology, Cumhuriyet University Medical School, 58140, Sivas, Turkey

    Sahende Elagoz

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  1. Tanseli Gonlugur
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  2. Feride Sapmaz
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  3. Ozgur Katrancioglu
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  4. Ugur Gonlugur
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Correspondence to Ugur Gonlugur.

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Gonlugur, T., Sapmaz, F., Katrancioglu, O. et al. Pulmonary lymphangitic sarcomatosis and a review of the literature. Clin Exp Metastasis 26, 399–402 (2009). https://doi.org/10.1007/s10585-008-9181-3

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  • DOI: https://doi.org/10.1007/s10585-008-9181-3

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