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Anorexia Nervosa in Adolescence: A Comprehensive Study of Multidimensional Factors Associated with Symptom Severity 1 Year Following the Diagnosis

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Abstract

The overarching goal of this study was to examine the unique contribution of psychological, familial, and friendship factors in explaining anorexia nervosa (AN) symptom severity 1 year following diagnosis among a sample of adolescent girls. A second objective was to determine whether friendship factors mediated the association between psychological and/or familial factors and AN symptom severity. This study included 143 adolescent girls under the age of 18 diagnosed with AN (M = 14.84, SD = 1.31). Participants were recruited from specialized eating disorder treatment programs. At admission (T1), participants completed a set of self-report questionnaires measuring psychological, familial, and friendship factors. AN symptom severity was assessed 1 year later (T2). Results of hierarchical regression analysis revealed that greater general psychological maladjustment at T1 (b = .26; se = .03; p = .00) was associated with greater AN symptom severity at T2. Greater alienation from friends at T1 (b = 1.20, se = .53, p = .03) also predicted greater AN symptom severity at T2, above and beyond the influence of adolescent girls’ general psychological maladjustment. Finally, the mediating role of alienation from friends in the association between general psychological maladjustment at T1 and AN symptom severity at T2 was also identified. AN is a multidimensional disorder with a prognosis that involves both psychological and social factors. The results stemming from the present study shed light on the role of peer as a mechanism through which general psychological maladjustment is linked to AN symptom severity 1 year following diagnosis.

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The ethics committees of the university hospital centers involved in the current study have very strict standards and do not allow data sharing.

References

  1. American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders: DSM-5, 5th edn. American Psychiatric Association, Washington

    Book  Google Scholar 

  2. Lantzouni E, Grady R (2021) Eating disorders in children and adolescents : a practical review and update for pediatric gynecologists. J Pediatr Adolesc Gynecol 34(3):281–287. https://doi.org/10.1016/j.jpag.2021.01.010

    Article  PubMed  Google Scholar 

  3. Steinhausen H-C, Jensen CM (2015) Time trends in lifetime incidence rates of first-time diagnosed anorexia nervosa and bulimia nervosa across 16 years in a danish nationwide psychiatric registry study: time trends in incidence rates of eating disorders. Int J Eat Disord 48(7):845–850. https://doi.org/10.1002/eat.22402

    Article  PubMed  Google Scholar 

  4. Couturier J, Kimber M, Szatmari P (2013) Efficacy of family-based treatment for adolescents with eating disorders: a systematic review and meta-analysis. Int J Eat Disord 46(1):3–11. https://doi.org/10.1002/eat.22042

    Article  PubMed  Google Scholar 

  5. Roux H, Chapelon E, Godart N (2013) Épidémiologie de l’anorexie mentale: Revue de la littérature. L’Encéphale 39(2):85–93. https://doi.org/10.1016/j.encep.2012.06.001

    Article  PubMed  Google Scholar 

  6. Steinhausen H-C (2009) Outcome of eating disorders. Child And Adolesc Psychiatric Clin N Am 18(1):225–242. https://doi.org/10.1016/j.chc.2008.07.013

    Article  Google Scholar 

  7. Black DW, Andreasen NC (2020) Introductory textbook of psychiatry, 7th edn. American Psychiatric Association Publishing, Washington. https://doi.org/10.1176/appi.books.9781615373758

    Book  Google Scholar 

  8. Cost J, Krantz MJ, Mehler PS (2020) Medical complications of anorexia nervosa. Clevel Clin J Med 87(6):361–366. https://doi.org/10.3949/ccjm.87a.19084

    Article  Google Scholar 

  9. Peebles R, Hardy KK, Wilson JL, Lock JD (2010) Are diagnostic criteria for eating disorders markers of medical severity? Pediatrics 125(5):e1193–e1201. https://doi.org/10.1542/peds.2008-1777

    Article  PubMed  Google Scholar 

  10. Sawyer SM, Whitelaw M, Le Grange D, Yeo M, Hughes EK (2016) Physical and psychological morbidity in adolescents with atypical anorexia nervosa. Pediatrics 137(4):e20154080. https://doi.org/10.1542/peds.2015-4080

    Article  PubMed  Google Scholar 

  11. Whitelaw M, Gilbertson H, Lee KJ, Sawyer SM (2014) Restrictive eating disorders among adolescent inpatients. Pediatrics 134(3):e758–e764. https://doi.org/10.1542/peds.2014-0070

    Article  PubMed  Google Scholar 

  12. Damon W, Lerner RM (eds) (2008) Child and adolescent development : an advanced course. Wiley, New York

    Google Scholar 

  13. Criscuolo M, Marchetto C, Chianello I, Cereser L, Castiglioni MC, Salvo P, Vicari S, Zanna V (2020) Family functioning, coparenting, and parents’ ability to manage conflict in adolescent anorexia nervosa subtypes. Fam Syst Health 38(2):151–161. https://doi.org/10.1037/fsh0000483

    Article  PubMed  Google Scholar 

  14. Garner DM (2004) Eating disorder inventory-3. Psychological Assessment Resources Inc., Lutz

    Google Scholar 

  15. Gruber M, König D, Holzhäuser J, Castillo DM, Blüml V, Jahn R, Leser C, Werneck-Rohrer S, Werneck H (2020) Parental feeding practices and the relationship with parents in female adolescents and young adults with eating disorders: a case control study. PLoS ONE 15(11):e0242518. https://doi.org/10.1371/journal.pone.0242518

    Article  PubMed  PubMed Central  Google Scholar 

  16. Tafà M, Cimino S, Ballarotto G, Bracaglia F, Bottone C, Cerniglia L (2017) Female adolescents with eating disorders, parental psychopathological risk and family functioning. J Child Fam Stud 26(1):28–39. https://doi.org/10.1007/s10826-016-0531-5

    Article  Google Scholar 

  17. Munro C, Randell L, Lawrie SM (2017) An integrative bio-psycho-social theory of anorexia nervosa : integrative bio-psycho-social theory of anorexia nervosa. Clin Psychol Psychother 24(1):1–21. https://doi.org/10.1002/cpp.2047

    Article  PubMed  Google Scholar 

  18. Pelletier Brochu J, Meilleur D, DiMeglio G, Taddeo D, Lavoie E, Erdstein J, Pauzé R, Pesant C, Thibault I, Frappier J-Y (2018) Adolescents’ perceptions of the quality of interpersonal relationships and eating disorder symptom severity: the mediating role of low self-esteem and negative mood. Eat Disord 26(4):388–406. https://doi.org/10.1080/10640266.2018.1454806

    Article  PubMed  Google Scholar 

  19. Nickerson AB, Nagle RJ (2005) Parent and peer attachment in late childhood and early adolescence. J Early Adolesc 25(2):223–249. https://doi.org/10.1177/0272431604274174

    Article  Google Scholar 

  20. Kaplan RM, Sallis JF, Patterson TL (1993) Health and human behavior. McGraw-Hill, New York

    Google Scholar 

  21. Westwood LM, Kendal SE (2012) Adolescent client views towards the treatment of anorexia nervosa: a review of the literature. J Psychiatr Ment Health Nurs 19(6):500–508. https://doi.org/10.1111/j.1365-2850.2011.01819.x

    Article  PubMed  Google Scholar 

  22. Leonidas C, Santos M (2014) Social support networks and eating disorders: an integrative review of the literature. Neuropsychiatric Dis Treat. https://doi.org/10.2147/NDT.S60735

    Article  Google Scholar 

  23. Bulik CM, Sullivan PF, Tozzi F, Furberg H, Lichtenstein P, Pedersen NL (2006) Prevalence, heritability, and prospective risk factors for anorexia nervosa. Arch Gen Psychiatry 63(3):305. https://doi.org/10.1001/archpsyc.63.3.305

    Article  PubMed  Google Scholar 

  24. Wade TD, Bulik CM, Neale M, Kendler KS (2000) Anorexia nervosa and major depression: shared genetic and environmental risk factors. Am J Psychiatry 157(3):469–471. https://doi.org/10.1176/appi.ajp.157.3.469

    Article  PubMed  Google Scholar 

  25. Keski-Rahkonen A, Raevuori A, Bulik CM, Hoek HW, Rissanen A, Kaprio J (2014) Factors associated with recovery from anorexia nervosa: a population-based study: factors associated with recovery from anorexia nervosa. Int J Eat Disord 47(2):117–123. https://doi.org/10.1002/eat.22168

    Article  PubMed  Google Scholar 

  26. Coyle EF, Fulcher M (2022) Social influences on gender development : theory and context. In: VanderLaan DP, Wong WI (eds) Gender and sexuality development. Springer, New York, pp 101–124. https://doi.org/10.1007/978-3-030-84273-4_4

    Chapter  Google Scholar 

  27. Kovacs M (2014) Children’s depression Inventory 2. Multi-Health Systems Inc., Toronto

    Book  Google Scholar 

  28. Beck AT, Steer RA, Brown GK (1996) BDI-II, Beck depression inventory: manual, 2nd edn. Psychological Corp., Harcourt Brace

    Google Scholar 

  29. March JS (1999) Multidimensional anxiety scale for children. Multi-Health Systems Inc., Toronto

    Google Scholar 

  30. Olson DH, Gorall DM, Tiesel JW (2004) Faces IV package. Life Innovations, Minneapolis

    Google Scholar 

  31. Armsden GC, Greenberg MT (1987) The inventory of parent and peer attachment : Individual differences and their relationship to psychological well-being in adolescence. J Youth Adolesc 16(5):427–454

    Article  PubMed  Google Scholar 

  32. Delgado L, Penelo E, Fornieles A, Brun-Gasca C, Ollé M (2016) Factorial structure and internal consistency of the inventory of parent and peer attachment for adolescents (IPPA) Spanish version. Universitas Psychologica 15:327–338

    Google Scholar 

  33. Lisinskiene A, Juskeliene V (2019) Links between adolescents’ engagement in physical activity and their attachment to mothers, fathers, and peers. Int J Environ Res Public Health 16(5):866. https://doi.org/10.3390/ijerph16050866

    Article  PubMed  PubMed Central  Google Scholar 

  34. Rockwood N, Hayes A (2020) Mediation, moderation, and conditional process analysis: regression-based approaches for clinical research. In: Roberts MC (ed) Handbook of research methods in clinical psychology. Blackwell Publishing Ltd., Hoboken, pp 396–414. https://doi.org/10.1002/9780470756980

    Chapter  Google Scholar 

  35. Racine SE, Wildes JE (2015) Emotion dysregulation and anorexia nervosa: an exploration of the role of childhood abuse. Int J Eat Disord 48(1):55–58. https://doi.org/10.1002/eat.22364

    Article  PubMed  Google Scholar 

  36. Weigel A, Löwe B, Kohlmann S (2019) Severity of somatic symptoms in outpatients with anorexia and bulimia nervosa. Eur Eat Disord Rev 27(2):195–204. https://doi.org/10.1002/erv.2643

    Article  PubMed  Google Scholar 

  37. Baumeister RF, DeWall CN, Ciarocco NJ, Twenge JM (2005) Social exclusion impairs self-regulation. J Pers Soc Psychol 88(4):589–604. https://doi.org/10.1037/0022-3514.88.4.589

    Article  PubMed  Google Scholar 

  38. Oliver KG, Huon GF, Zadro L, Williams KD (2001) The role of interpersonal stress in overeating among high and low disinhibitors. Eat Behav 2(1):19–26. https://doi.org/10.1016/S1471-0153(00)00020-9

    Article  PubMed  Google Scholar 

  39. Stroud LR, Tanofsky-Kraff M, Wilfley DE, Salovey P (2000) The Yale Interpersonal Stressor (YIPS): affective, physiological, and behavioral responses to a novel interpersonal rejection paradigm. Ann Behav Med 22(3):204–213. https://doi.org/10.1007/BF02895115

    Article  PubMed  Google Scholar 

  40. Murphy R, Straebler S, Basden S, Cooper Z, Fairburn CG (2012) Interpersonal psychotherapy for eating disorders. Clin Psychol Psychother 19(2):150–158. https://doi.org/10.1002/cpp.1780

    Article  PubMed  Google Scholar 

  41. Caron J, Guay S (2006) Soutien social et santé mentale: concept, mesures, recherches récentes et implications pour les cliniciens. Santé mentale au Québec 30(2):15–41. https://doi.org/10.7202/012137ar

    Article  Google Scholar 

  42. Sonneville KR, Lipson SK (2018) Disparities in eating disorder diagnosis and treatment according to weight status, race/ethnicity, socioeconomic background, and sex among college students. Int J Eat Disord 51(6):518–526. https://doi.org/10.1002/eat.22846

    Article  PubMed  Google Scholar 

  43. Castro-Fornieles J, Casulà V, Saura B, Martínez E, Lazaro L, Vila M, Plana MT, Toro J (2007) Predictors of weight maintenance after hospital discharge in adolescent anorexia nervosa. Int J Eat Disord 40(2):129–135. https://doi.org/10.1002/eat.20340

    Article  PubMed  Google Scholar 

  44. Collin P, Power K, Karatzias T, Grierson D, Yellowlees A (2010) The effectiveness of, and predictors of response to, inpatient treatment of anorexia nervosa. Eur Eat Disord Rev 18(6):464–474. https://doi.org/10.1002/erv.1026

    Article  PubMed  Google Scholar 

  45. Errichiello L, Iodice D, Bruzzese D, Gherghi M, Senatore I (2016) Prognostic factors and outcome in anorexia nervosa: a follow-up study. Eat Weight Disord-Stud Anorexia Bulimia Obes 21(1):73–82. https://doi.org/10.1007/s40519-015-0211-2

    Article  Google Scholar 

  46. Fichter MM, Quadflieg N, Hedlund S (2006) Twelve-year course and outcome predictors of anorexia nervosa. Int J Eat Disord 39(2):87–100. https://doi.org/10.1002/eat.20215

    Article  PubMed  Google Scholar 

  47. Salbach-Andrae H, Lenz K, Simmendinger N, Klinkowski N, Lehmkuhl U, Pfeiffer E (2008) Psychiatric comorbidities among female adolescents with anorexia nervosa. Child Psychiatry Hum Dev 39(3):261–272

    Article  PubMed  Google Scholar 

  48. Tasaka K, Matsubara K, Takamiya S, Ishikawa S, Iwata A, Nigami H (2017) Long-term follow up of hospitalized pediatric anorexia nervosa restricting type. Pediatr Int 59(4):482–489. https://doi.org/10.1111/ped.13194

    Article  PubMed  Google Scholar 

  49. Taquet M, Geddes JR, Luciano S, Harrison PJ (2021) Incidence and outcomes of eating disorders during the COVID-19 pandemic. Br J Psychiatry. https://doi.org/10.1192/bjp.2021.105

    Article  PubMed  PubMed Central  Google Scholar 

  50. Zipfel S, Schmidt U, Giel KE (2022) The hidden burden of eating disorders during the COVID-19 pandemic. Lancet Psychiatry 9(1):9–11. https://doi.org/10.1016/S2215-0366(21)00435-1

    Article  PubMed  Google Scholar 

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Funding

The research project was funded by the Canadian Institute of Health Research.

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IT and KP wrote the article and performed the statistical analyses. All other authors reviewed the article and contributed to the study (e.g., data collection).

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Correspondence to Isabelle Thibault.

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The authors declare no conflict of interest.

Ethical Approval

This project received ethical approval from all university hospital centers (Centre hospitalier universitaire de Sherbrooke, Montreal Children’s Hospital McGill University Health Centre, Centre hospitalier universitaire Sainte-Justine, Centre hospitalier universitaire de Québec Université Laval) in which the research was conducted.

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Thibault, I., Pascuzzo, K., Pesant, C. et al. Anorexia Nervosa in Adolescence: A Comprehensive Study of Multidimensional Factors Associated with Symptom Severity 1 Year Following the Diagnosis. Child Psychiatry Hum Dev (2023). https://doi.org/10.1007/s10578-023-01599-6

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