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Risk and Resilience Measures Related to Psychopathology in Youth

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Abstract

Childhood adversity places youth at risk for multiple negative outcomes. The current study aimed to understand how a constellation of risk and resilience factors influenced mental health outcomes as a function of adversities: socioeconomic status (SES) and traumatic stressful events (TSEs). Specifically, we examined outcomes related to psychosis and mood disorders, as well as global clinical functioning. The current study is a longitudinal follow up of 140 participants from the Philadelphia Neurodevelopmental Cohort (PNC) assessed for adversities at Time 1 (Mean age: 14.11 years) and risk, resilience, and clinical outcomes at Time 2 (mean age: 21.54 years). In the context of TSE, a limited set of predictors emerged as important; a more diverse set of moderators emerged in the context of SES. Across adversities, social support was a unique predictor of psychosis spectrum diagnoses and global functioning; emotion dysregulation was an important predictor for mood diagnoses. The current findings underscore the importance of understanding effects of childhood adversity on maladaptive outcomes within a resilience framework.

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Funding

National Institute of Mental Health, MH089983, Raquel E. Gur, MH117014, Raquel E. Gur, MH096891, Raquel E. Gur, Lifespan Brain Institute.

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Authors and Affiliations

  1. Lifespan Brain Institute, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA

    Lauren K. White, Ran Barzilay, Tyler M. Moore, Monica E. Calkins, Jason D. Jones, Megan M. Himes, Jami F. Young, Ruben C. Gur & Raquel E. Gur

  2. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA

    Lauren K. White, Ran Barzilay, Tyler M. Moore, Monica E. Calkins, Jason D. Jones, Jami F. Young, Ruben C. Gur & Raquel E. Gur

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  1. Lauren K. White
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Correspondence to Lauren K. White.

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White, L.K., Barzilay, R., Moore, T.M. et al. Risk and Resilience Measures Related to Psychopathology in Youth. Child Psychiatry Hum Dev 54, 961–972 (2023). https://doi.org/10.1007/s10578-021-01296-2

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