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The Possible Roles of Brain Pericytes in Brain Ischemia and Stroke

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Abstract

Brain pericytes regulate a variety of functions, such as microcirculation, angiogenesis, and the blood brain barrier in the brain. Recent studies have also shown that they are pluripotent in a manner similar to mesenchymal stem cells. Since, brain pericytes actively control these functions, these cells probably play an important role not only during brain ischemia, but also in the post-stroke period.

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Acknowledgments

This study was partially supported by Coordination, Support and Training Program for Translational Research and Grand-in-Aid for Scientific Research (C 19590992, C 22590937) from The Japanese Ministry of Education, Culture, Sports, Science and Technology. We are grateful to Dr. Kuniyuki Nakamura for his helpful suggestions.

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  1. Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan

    Masahiro Kamouchi, Tetsuro Ago, Junya Kuroda & Takanari Kitazono

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  1. Masahiro Kamouchi
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  2. Tetsuro Ago
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Correspondence to Masahiro Kamouchi.

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Kamouchi, M., Ago, T., Kuroda, J. et al. The Possible Roles of Brain Pericytes in Brain Ischemia and Stroke. Cell Mol Neurobiol 32, 159–165 (2012). https://doi.org/10.1007/s10571-011-9747-5

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