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Calcium Binding Proteins Immunoreactivity in the Rat Basolateral Amygdala Following Myocardial Infarction

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Abstract

In this study, we examined changes in immunoreactivities of calcium binding proteins, such as parvalbumin (PV), calbindin (CB), and calretinin (CR), in the rat basolateral amygdala (BLA) 14 days after myocardial infarction (MI). In the MI-operated group, numbers of PV and CB immunoreactive (+) neurons in the BLA were significantly reduced compared to those in the sham-operated group. However, numbers of CR+ neurons were slightly, not significantly, reduced in the MI-operated group. These results indicate that MI may decrease the immunoreactivities of PV and CB, not CR, in the rat BLA.

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Acknowledgments

The authors would like to thank Mr. Seung Uk Lee and Ms. Hyun Sook Kim for their technical help in this study. This work was supported by the stem cell research program of Ministry of Science & Technology, grants (M10641450002-07N4145-00210) and was also supported by the Brain Science (Neurobiology) Program of Ministry of Science and Technology (Grant 2004-01466) to PDR.

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Authors and Affiliations

  1. Department of Anatomy and Neurobiology, College of Medicine, Hallym University, Chuncheon, 200-702, South Korea

    Choong Hyun Lee, Jung Hoon Choi, Ki-Yeon Yoo, Ok Kyu Park & Moo-Ho Won

  2. Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul, 151-742, South Korea

    In Koo Hwang

  3. Laboratory of Veterinary Pharmacology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul, 151-742, South Korea

    Tae Hee Han, So Yeong Lee & Pan Dong Ryu

  4. Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University, Chuncheon, 200-702, South Korea

    Moo-Ho Won

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  1. Choong Hyun Lee
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  2. In Koo Hwang
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  3. Jung Hoon Choi
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  4. Ki-Yeon Yoo
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  5. Tae Hee Han
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  7. So Yeong Lee
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  9. Moo-Ho Won
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Correspondence to In Koo Hwang or Moo-Ho Won.

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Lee, C.H., Hwang, I.K., Choi, J.H. et al. Calcium Binding Proteins Immunoreactivity in the Rat Basolateral Amygdala Following Myocardial Infarction. Cell Mol Neurobiol 30, 333–338 (2010). https://doi.org/10.1007/s10571-009-9465-4

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  • DOI: https://doi.org/10.1007/s10571-009-9465-4

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