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Modelling of water absorption kinetics and biocompatibility study of synthesized cellulose nanofiber-assisted starch-graft-poly(acrylic acid) hydrogel nanocomposites

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Abstract

To prepare superabsorbent hydrogels, starch-graft-poly(acrylic acid) reinforced by cellulose nanofibers (CNF), was synthesized through free radical graft polymerization. The results of its biocompatibility tests exhibited that by increasing incubation time from 1 to 5 days, the numbers of living cells were increased on both reinforced and unreinforced hydrogels. However, the fraction of cells on the surfaces of the reinforced hydrogel is comparable to unreinforced samples. The swelling amounts in NaCl, CaCl2, and AlCl3 solutions were 193 ± 9, 110 ± 8, and 99 ± 7 (gwater/gabsorbent) for 5 wt% CNF-reinforced hydrogels and 109 ± 8, 62 ± 7, and 56 ± 6 (gwater/gabsorbent) for unreinforced hydrogels, respectively. Compressive strength and Young’s modulus of 5 wt% CNF-assisted hydrogels were also 63.3 and 31.6 kPa corresponding to 69% and 140% improvements compared with unreinforced one. The graft polymerization of acrylic acid monomer was controlled by monomer content and cross-linking percentage, in order to achieve the highest swelling capacity for hydrogels. Hydrogel swelling in water was 312 gwater/gabsorbent for unreinforced hydrogel and 523 gwater/gabsorbent for 5 wt% CNF-reinforced sample and water absorption kinetics results was in agreement with the pseudo-second-order model. The prepared CNF-reinforced starch-graft-poly(acrylic acid) hydrogels can be used in a wide range of medical application due to the enhanced hydrophilicity, mechanical strength, and biocompatibility.

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Acknowledgments

Financial support of the Isfahan University of Technology is gratefully appreciated. We also kindly appreciate Mr. Pejman Heidarian’s effort for his guidance on perfecting the language of this manuscript.

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  1. Department of Chemical Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran

    Nooshin Bahadoran Baghbadorani, Tayebeh Behzad, Mohammad Hossein Karimi Darvanjooghi & Nasrin Etesami

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  1. Nooshin Bahadoran Baghbadorani
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  2. Tayebeh Behzad
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  3. Mohammad Hossein Karimi Darvanjooghi
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Correspondence to Tayebeh Behzad.

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Bahadoran Baghbadorani, N., Behzad, T., Karimi Darvanjooghi, M.H. et al. Modelling of water absorption kinetics and biocompatibility study of synthesized cellulose nanofiber-assisted starch-graft-poly(acrylic acid) hydrogel nanocomposites. Cellulose 27, 9927–9945 (2020). https://doi.org/10.1007/s10570-020-03511-0

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