A pH indicating carboxymethyl cellulose/chitosan sponge for visual monitoring of wound healing

Tu, Chao; Zhang, Run-dong; Yan, Chao; Guo, Yi; Cui, Li

doi:10.1007/s10570-019-02378-0

Original Research
Published: 27 March 2019

A pH indicating carboxymethyl cellulose/chitosan sponge for visual monitoring of wound healing

Chao Tu¹,
Run-dong Zhang¹,
Chao Yan¹,
Yi Guo¹ &
Li Cui ORCID: orcid.org/0000-0002-3648-3927¹

Cellulose volume 26, pages 4541–4552 (2019)Cite this article

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Abstract

A type of carboxymethyl cellulose/chitosan composite sponge that is able to indicate pH changes was prepared and characterized. This sponge, dyed with the natural dye cyanine, showed a rather rapid response by changing from blue to green as the solution pH changed from 4 to 8. This visible color change indicated that the sponge could be a pH sensor with high sensitivity. The carboxymethyl cellulose/chitosan composite sponges exhibited a good air permeability and high porosity because the sponge’s pores were all open and interconnected. The porosity, the moisture vapor transmission rate, and the water vapor permeability all increased as the chitosan content increased. The chitosan microparticles added in carboxymethyl cellulose reinforced the composite sponge and improved its antibacterial activity. The cyanine dyed carboxymethyl cellulose/chitosan sponges have substantial potential as wound-healing monitors.

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Authors and Affiliations

Hubei Key Laboratory of Biomass Fibers and Eco-dyeing & Finishing, Wuhan Textile University, Wuhan, China
Chao Tu, Run-dong Zhang, Chao Yan, Yi Guo & Li Cui

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Chao Tu
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Run-dong Zhang
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Chao Yan
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Yi Guo
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Li Cui
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Correspondence to Yi Guo or Li Cui.

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Tu, C., Zhang, Rd., Yan, C. et al. A pH indicating carboxymethyl cellulose/chitosan sponge for visual monitoring of wound healing. Cellulose 26, 4541–4552 (2019). https://doi.org/10.1007/s10570-019-02378-0

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Received: 19 December 2018
Accepted: 12 March 2019
Published: 27 March 2019
Issue Date: 15 May 2019
DOI: https://doi.org/10.1007/s10570-019-02378-0

Keywords

pH indicating
Cyanine
Carboxymethyl cellulose
Chitosan
Sponge