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Towards unnatural xylan based polysaccharides: reductive amination as a tool to access highly engineered carbohydrates

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Abstract

Low molecular weight xylan was modified at the reducing end with mono and bifunctional amines. Characterization by means of elemental analysis, nmr spectroscopy and mass spectrometry proved the success of the highly selective reaction. Modified xylan containing amino groups at the reducing end are capable to react with unmodified xylan and cellodextrins. The structure of the products obtained was proved by NMR spectroscopy. Size exclusion chromatography and mass spectrometry verified the increased molar mass of the head-head linked polysaccharides.

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Acknowledgments

The authors gratefully acknowledge Anja Baumgärtel from the work group of Prof. US Schubert for her efforts to acquire MALDI TOF mass spectra, Marcel Meiland for the preparation of cellodextrins and the Bene Pharmachem (Geretsried) for the generous financial support.

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  1. Center of Excellence for Polysaccharide Research, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University of Jena, Humboldtstr. 10, 07743, Jena, Germany

    Stephan Daus, Thomas Elschner & Thomas Heinze

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  1. Stephan Daus
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  2. Thomas Elschner
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  3. Thomas Heinze
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Correspondence to Thomas Heinze.

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Daus, S., Elschner, T. & Heinze, T. Towards unnatural xylan based polysaccharides: reductive amination as a tool to access highly engineered carbohydrates. Cellulose 17, 825–833 (2010). https://doi.org/10.1007/s10570-010-9421-y

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  • DOI: https://doi.org/10.1007/s10570-010-9421-y

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