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Novel Brønsted Acidic Ionic Liquid ([CMIM][CF3COO]) Prompted Multicomponent Hantzsch Reaction for the Eco-Friendly Synthesis of Acridinediones: An Efficient and Recyclable Catalyst

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Abstracts

A novel, highly efficient and recyclable Brønsted acidic ionic liquid ([CMIM][CF3COO]) has been successfully implemented for the synthesis of acridinediones in aqueous media. Recyclability of novel catalyst, high yields, use of environmentally benign aqueous media as solvent, simple product isolation, high atom economy and sidestep to column chromatography are the noteworthy features of this protocol. This protocol is competent for producing wide library of acridinediones in good to excellent yields. Furthermore, molecular structure and relative stereochemistry of 4c and 4s derivatives were confirmed by single-crystal X-ray diffraction.

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Acknowledgments

The authors are thankful to Department of Chemistry, Shivaji University, Kolhapur for spectral measurements. D.R.Patil is grateful to the UGC New Delhi for awarding him a Junior Research Fellowship [F.No. 41-211/2012(SR)]. The authors are also grateful to Department of Chemistry, IIT Madras, Chennai and Department of Physics & Electronics, University of Jammu, for providing single crystal analysis data of compound 4c and 4s (CCDC 965866, 965867).

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Authors and Affiliations

  1. Heterocyclic Research Laboratory, Department of Chemistry, Shivaji University, Kolhapur, MS, 416 004, India

    Dayanand Patil, Dattatray Chandam, Abhijeet Mulik, Surybala Jagadale & Madhukar Deshmukh

  2. Department of Agrochemicals and Pest Management, Shivaji University, Kolhapur, MS, 416 004, India

    Prasad Patil

  3. X-ray Crystallography Laboratory, Department of Physics & Electronics, University of Jammu, Jammu Tawi, 180 006, India

    Rajni Kant & Vivek Gupta

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  1. Dayanand Patil
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Correspondence to Madhukar Deshmukh.

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Patil, D., Chandam, D., Mulik, A. et al. Novel Brønsted Acidic Ionic Liquid ([CMIM][CF3COO]) Prompted Multicomponent Hantzsch Reaction for the Eco-Friendly Synthesis of Acridinediones: An Efficient and Recyclable Catalyst. Catal Lett 144, 949–958 (2014). https://doi.org/10.1007/s10562-014-1202-z

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